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TranscriptomicsTranscription profiling of skeletal muscle from diabetic or non-diabetic Mexican Americans with or without a family history of diabetes
Type 2 diabetes mellitus (DM) is characterized by insulin resistance and pancreatic beta-cell dysfunction. In high-risk subjects, the earliest detectable abnormality is insulin resistance in skeletal muscle. Impaired insulin-mediated signaling, gene expression, and glycogen synthesis, and accumulati...
ORGANISM(S): Homo sapiens 
2007-06-28 | E-CBIL-28 | biostudies-arrayexpress
UnknownAre reaching and grasping effector-independent? Similarities and differences in reaching and grasping kinematics between the hand and foot.
Not available
S-EPMC9142431 | biostudies-literature
UnknownA multimodal MRI study of the hippocampus in medication-naive children with ADHD: what connects ADHD and depression?
Not available
S-EPMC4195849 | biostudies-literature
ProteomicsMechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination
Homologous recombination (HR) repairs double-stranded DNA breaks (DSBs). The DSBs are resected to yield single-stranded DNA (ssDNA) that are coated by Replication Protein A (RPA). Rad51 is a recombinase and catalyzes strand invasion and the search for homology. However, it binds to ssDNA with lower ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-07-28 | PXD065573 | Pride
Cross-linking Lc-msms 
UnknownDistant lymph nodes compensate for resected tumor-draining lymph nodes during cancer immunotherapy.
Not available
S-EPMC10541098 | biostudies-literature
TranscriptomicsTranscription profiling of Drosophila antennal, eye, leg and wing discs with wild type or eyeless ectopic expression
The discovery of direct downstream targets of transcription factors (TFs) is necessary for understanding the genetic mechanisms underlying complex, highly regulated processes such as development. In this report, we have used a combinatorial strategy to conduct a genome-wide search for novel direct ...
ORGANISM(S): Drosophila melanogaster 
2007-09-28 | E-GEOD-4008 | biostudies-arrayexpress
ProteomicsAndrogen receptor RIME in prostate cancer cells
Androgen receptor (AR) is a master transcription factor that drives prostate cancer (PCa) development and progression. Alterations in the expression or activity of AR coregulators significantly impact the disease's outcome. To identify all the essential components of the AR coregulator complex, we u...
ORGANISM(S): Homo sapiens (Human) 
2022-07-12 | PXD031273 | Pride
Androgen receptor Prostate cancer Rime Cofactors 
ProteomicsLow Dose Radiation Induces New Protein Synthesis that Promotes Cancer Radiotherapy Resistance
Radiotherapy (RT) is a cornerstone of cancer treatment; however, its efficacy is frequently hampered by its adverse effects on normal tissues. By studying the effects of high-dose radiotherapy (HDRT) and low-dose radiotherapy (LDRT), we found that cancer cells adapt distinct responses to these doses...
ORGANISM(S): Homo Sapiens 
2026-02-26 | PXD074928 |
UnknownImpact of neoadjuvant chemotherapy on short-term outcomes after simple and complex minimally invasive minor hepatectomy for colorectal liver metastases: A propensity-score matched and coarsened exact matched study.
Not available
S-EPMC12360403 | biostudies-literature
UnknownImpact of liver cirrhosis, the severity of cirrhosis, and portal hypertension on the outcomes of minimally invasive left lateral sectionectomies for primary liver malignancies.
Not available
S-EPMC10986843 | biostudies-literature
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