Sort   by:  
 Page size 
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
ProteomicsThe label-free quantitative proteomic of EDB(+)FN1 and EDB(-)FN1
IP-MS assays of EDB(+)FN1 with a Flag epitope tag and EDB(-)FN1 with a His epitope tag. an equal amount of protein solution from each IP sample, the volume was adjusted to match the consistency of the original lysate.
ORGANISM(S): Homo Sapiens 
PXD053745 |
ProteomicsProteogenomic landscape of clear cell renal cell carcinoma response to tyrosine kinase inhibitor
We performed proteomic analysis of 115 ccRCC patients samples undergoing sunitinib treatment.
ORGANISM(S): Homo Sapiens 
PXD042844 |
ProteomicsProteogenomic Characterization of MiT Family Translocation Renal Cell Carcinoma
Comprehensive proteogenomic analysis of Microphthalmia Transcription Factor (MiT) family translocation renal cell carcinoma (tRCC) tumor and normal adjacent tissues was performed to elucidate the molecular landscape of these tumors.
ORGANISM(S): Homo Sapiens 
PXD035377 |
ProteomicsA Proteogenomic Analysis of Clear Cell Renal Cell Carcinoma in a Chinese Population
We performed proteomic analysis of 232 ccRCC patients samples.
ORGANISM(S): Homo Sapiens 
2022-04-16 | PXD030344 |
ProteomicsLithocholic acid targets TULP3-Sirtuins to deacetylate v-ATPase and activate AMPK
Lithocholic acid (LCA), accumulated in mammals during calorie restriction (CR), can activate AMP-activated protein kinase (AMPK) and slow down ageing1. However, how LCA is signalled to activate AMPK and elicit the biological effects is unclear. Here, we show that LCA can enhance the activity of sirt...
ORGANISM(S): Homo Sapiens Mus Musculus 
PXD056134 |
ProteomicsLow glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
This project identified the interacting proteins of p53 under glucose starvation in HEK293 cells.
ORGANISM(S): Homo Sapiens 
2023-04-04 | PXD041361 |
ProteomicsThe aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
The activity of 5’-adenosine monophosphate-activated protein kinase (AMPK) is inversely correlated with the cellular availability of glucose. When glucose levels are low, the glycolytic enzyme aldolase is not bound to fructose-1,6-bisphosphate (FBP) and, instead, signals to activate lysosomal AMPK. ...
ORGANISM(S): Oryctolagus Cuniculus 
2022-08-10 | PXD035968 |
UnknownGenome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH.
Not available
S-EPMC10790310 | biostudies-literature
Sort   by:  
 Page size