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MetabolomicsEffects of Platycodins Folium on Depression in Mice Based on a UPLC-Q/TOF-MS Serum Assay and Hippocampus Metabolomics
Major depressive disorder (MDD), also known as depression, is a state characterized by low mood and aversion to activity. Platycodins Folium (PF) is the dried leaf of Platycodon grandiflorum, with anti-inflammatory and antioxidative activities. Our previous research suggested that PF was rich in fla...
2020-06-03 | MTBLS952 | MetaboLights
UnknownSOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1.
Not available
S-EPMC12209067 | biostudies-literature
ProteomicsRevealing Stress Granule Compositional Heterogeneity through Antibody-Guided Proximity Labeling
Stress granules (SGs), transient nonmembranous cytoplasmic condensates that formed in response to cellular stresses, require precise characterization to unravel their cell-type and stressspecific protein compositions. This study introduced a G3BP1 antibody-guided proximity labeling (Ab-PL) method to...
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse) 
2025-11-21 | PXD070978 | JPOST Repository
ProteomicsAn automated intact glycopeptide enrichment method for serum site-specific N-glycoproteomic analysis
We developed an automated glycopeptide enrichment method for the analysis of serum site-specific N-glycoproteome. This automated method allowed for processing one sample within 20 min. It showed higher enrichment specificity, more intact glycopeptide identifications, and better quantitative reproduc...
ORGANISM(S): Homo Sapiens (human) 
2021-04-06 | PXD025151 | JPOST Repository
ProteomicsImpaired O-GlcNAcylation rather than N-glycosylation caused by AtAGM deficiency leads to growth variations in Arabidopsis thaliana
To reveal the function of N-acetylglucosamine phosphate mutase (AGM) and UDP-GlcNAc in Arabidopsis growth, WT and a T-DNA insertional mutant Atagm-2 were used for proteomic analysis.
ORGANISM(S): Arabidopsis Thaliana 
2021-03-25 | PXD024977 |
ProteomicsThe mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling
MAVS-Turbo ID IP in HEK293T cells treated with or without SeV
ORGANISM(S): Homo Sapiens 
2020-12-08 | PXD023002 |
ProteomicsOne-Step Chemoenzymatic Labeling and Oxime-Reversible Enrichment for O-GlcNAc Profiling in Oxidative Stress
Chemoenzymatic labeling has greatly advanced O-GlcNAc proteomics, yet existing strategies using azide-modified donors (e.g., UDP-GalNAz) require multi-step click-based workflows that introduce substantial sample loss and limit sensitivity toward low-abundance targets. While recent one-step labeling ...
ORGANISM(S): Homo Sapiens 
2026-01-06 | PXD072723 |
ProteomicsHuman serum glycoproteome - Glyco-Decipher
Identification results of peptide-spectrum matches supporting Glyco-Decipher manuscript (Glyco-Decipher: Glycan database-independent peptide matching enables discovery of new glycans and in-depth characterization of site-specific N-glycosylation). Recently, several elegant bioinformatics tools have ...
ORGANISM(S): Homo Sapiens 
2023-09-25 | PXD045630 |
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