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UnknownExosome-mediated delivery of RBP-J decoy oligodeoxynucleotides ameliorates hepatic fibrosis in mice.
Not available
S-EPMC8825583 | biostudies-literature
UnknownA Retrospective Study on the Significance of Liver Biopsy and Hepatitis B Surface Antigen in Chronic Hepatitis B Infection.
Not available
S-EPMC4778991 | biostudies-literature
MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
ProteomicsProteomics in biomanufacturing control: Protein dynamics of CHO-K1 cells and conditioned media during apoptosis and necrosis
Cell viability has a critical impact on product quantity and quality during the biomanufacturing of therapeutic proteins. An advanced understanding of changes in the cellular and conditioned media proteomes upon cell stress and death is therefore needed for improved bioprocess control. Here, a high ...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2018-02-27 | PXD008297 | Pride
Proteomics Cho Keywords: biomanufacturing Necrosis Apoptosis 2d-lc-mse 
MetabolomicsRegulatory T cells promote endurance exercise adaptation by shielding muscle mitochondria from damage

Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...

2023-10-10 | MTBLS8391 | MetaboLights
UnknownHand, foot, and mouth disease in China, 2008-12: an epidemiological study.
Not available
S-EPMC4035015 | biostudies-literature
TranscriptomicsSolanum lycopersicumTranscriptome or Gene expression
Gene expression in wild-type fruit. Strand-specific RNA-Seq data was used to calculate the gene expression value (RPKM) in four wild-type fruit developmental stages including immature fruit at 17DPA, mature green fruit (seeds development completes) at 39DPA, breaker fruit (onset of ripening) at 42DP...
ORGANISM(S): Solanum lycopersicum 
2011-10-07 | E-MTAB-4818 | biostudies-arrayexpress
ProteomicsIsolated Mitochondria from Cold and TN Mice LC MS/MS
: Proteomic Analysis from isolated mitochondria from the brown fat of C57BL6/J mice that were exposed to cold or thermoneutrality for 8 days.
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD043251 | Pride
Mitochondria Thermoneutrality Cold Nipsnap1 
MetabolomicsSerine synthesis pathway enzyme PHGDH is critical for muscle cell biomass, anabolic metabolism and mTORC1 signaling

Cells use glycolytic intermediates for anabolism e.g., via the serine synthesis and pentose phosphate pathways. However, we still understand poorly how these metabolic pathways contribute to skeletal muscle cell biomass generation. The first aim of this study was therefore to identify enzymes tha...

2025-03-21 | MTBLS8854 | MetaboLights
UnknownDown-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2.
Not available
S-EPMC6704446 | biostudies-literature
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