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DNA replication is initiated at multiple sites or origins enriched with AT-rich sequences at various times during the S-phase. While current studies of genome-wide DNA replication profiles have focused on the timing of replication and the location of origins, the efficiency of replication/firing at...
ORGANISM(S): Schizosaccharomyces pombe 
Adipose tissue is critical in the development of Metabolically unhealthy obesity (MUO). This study aimed to investigate the different responses and regulations of subcutaneous (SA) and visceral adipose tissue (VA) to MUO by integrative proteome and lysine acetylation (Kac) analyses. This study signi...
ORGANISM(S): Homo Sapiens 
2024-10-15 | PXD056800 |
The raw data of coal workers pneumoconiosis serum metabolomics
ORGANISM(S): Homo Sapiens 
2025-09-17 | PXD068448 |
In order to research the relationship between neurological sequelae of COVID-19 and acetylation of brain cortexes, we reported for the first time the acetylome in the brain cortex of the K18-hACE2 infected mouse model, and the difference between the SARS-CoV-2 infection group and the control group, ...
ORGANISM(S): Mus Musculus 
2022-09-20 | PXD036853 |
The LC-MS/MS raw data from negative mode of umbilical cord blood from pregnant women
ORGANISM(S): Homo Sapiens 
2026-05-19 | PXD078591 |
The Omicron variant, mutated from the original SARS-CoV-2 strain, is still circulating worldwide. We performed LC-MS based proteome and phosphoproteome analysis using lung tissues separated from rhesus monkeys, which were infected with Omicron, the original virus or one of the VOCs, the Delta varian...
ORGANISM(S): Macaca Mulatta 
2023-12-12 | PXD047779 |
We present the first comprehensive proteomic and phosphoproteomic atlas of nine major organs of the Chinese hamster (Cricetulus griseus). A total of 14,219 proteins, 11,828 phosphorylated proteins, and 47,122 phosphorylation sites were identified, revealing distinct inter-organ molecular features.
ORGANISM(S): Cricetulus Griseus 
2025-10-04 | PXD069241 |
Abdominal Aortic Aneurysm (AAA) is a fatal vascular disease characterized by abnormal expansion of the arterial wall and a high risk of rupture. Current treatments for AAA primarily rely on surgical intervention, while effective pharmacological therapies have yet to be developed. The major bottlenec...
ORGANISM(S): Mus Musculus 
2025-02-17 | PXD060895 |
Inhalation of crystalline silica dust induces incurable lung damage, silicosis and pulmonary fibrosis. However, the mechanisms of the lung injury remain poorly understood, with limited therapeutic options aside from lung transplantation. Post-translational modifications can regulate the function of...
ORGANISM(S): Mus Musculus 
2024-02-04 | PXD049146 |
Macaque study was conducted in an ABSL-3 facility, adhering to protocols approved by the Institutional Animal Care and Use Committee (IACUC) under the guidelines of the Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences (Approval Number XJ23004). All animals were single-hous...
ORGANISM(S): Macaca Mulatta 
2024-10-12 | PXD056753 |
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