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UnknownHER3 functions as an effective therapeutic target in triple negative breast cancer to potentiate the antitumor activity of gefitinib and paclitaxel.
Not available
S-EPMC10504712 | biostudies-literature
UnknownPea3 expression promotes the invasive and metastatic potential of colorectal carcinoma.
Not available
S-EPMC4265596 | biostudies-literature
UnknownHER3 targeting augments the efficacy of panobinostat in claudin-low triple-negative breast cancer cells.
Not available
S-EPMC10400567 | biostudies-literature
UnknownIn vivo base editing extends lifespan of a humanized mouse model of prion disease.
Not available
S-EPMC12003183 | biostudies-literature
UnknownIncreased inflammatory low-density neutrophils in severe obesity and effect of bariatric surgery: Results from case-control and prospective cohort studies.
Not available
S-EPMC8897585 | biostudies-literature
ProteomicsProteome Dataset for Adult-derived Mouse Microglia
We report methods development for quantitative proteomic analysis of samples with limited number of cells. The improvements include suspension trapping (S-Trap) for sample processing, longer analytical column length (75cm), and a segmented data dependent acquisition approach. The modified approach w...
ORGANISM(S): Mus musculus (Mouse) 
2019-04-18 | PXD012006 | Pride
Neuroinflammation Img cells Proteomics Mass spectrometry Microglia Dataset brief Glia 
ProteomicsProteomic analysis of alcohol and LPS-treated primary mouse microglia
Microglia, the resident immune cells of the brain, can exhibit a broad range of activation phenotypes, many of which have been implicated in several diseases and disorders of the central nervous system including alcohol use disorders and disorders. By utilizing a method optimized for sensitive and ...
ORGANISM(S): Mus musculus (Mouse) 
2020-04-07 | PXD014466 | Pride
Lps Neuroinflammation Ethanol Alcohol Microglia Glia 
UnknownDevelopment of Effective Therapeutics Targeting HER3 for Cancer Treatment.
Not available
S-EPMC6425631 | biostudies-literature
UnknownHER3 promotes triple-negative breast cancer progression by upregulating PHF8 via miR-34b-5p-dependent mechanism.
Not available
S-EPMC12592479 | biostudies-literature
ProteomicsIntegrated Multi-Omic Analysis Reveals KDM5B as a Regulator of Microglial Reactivity to Immunomodulatory Stimuli
Microglia maintain brain homeostasis through coordinated pathways, including cell migration, phagocytosis, and secretion of immune-related signaling factors. Microglial reactivity is associated with a variety of functional outcomes that are highly context-dependent with epigenetic regulation through...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-02 | PXD058485 | Pride
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