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ProteomicsPhosphoproteomics Data of pancreatic cancers cells treated with anlotinib
Aberrant regulation of angiogenesis involves in the growth and metastasis of tumors, but angiogenesis inhibitors fail to improve overall survival of pancreatic cancer patients in previous phase III clinical trials. A comprehensive knowledge of the mechanism of angiogenesis inhibitors against pancrea...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023345 | Pride
Phosphoproteomics data Anlotinib Pancreatic cancer 
ProteomicsPancreatic cancer cells treated with anlotinib
Aberrant regulation of angiogenesis involves in the growth and metastasis of tumors, but angiogenesis inhibitors fail to improve overall survival of pancreatic cancer patients in previous phase III clinical trials. A comprehensive knowledge of the mechanism of angiogenesis inhibitors against pancrea...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023344 | Pride
Pancreatic cancer Anlotinib 
ProteomicsThe antibacterial mechanism of sertindole against Staphylococcus aureus
Clinically isolated MRSA strain was inoculated and cultured to exponential growth phase (OD600 at 0.5) in TSB and divided into two groups, the control group and the drug treated group. Sertindole was added to the drug treated group until a final concentration of 1/2× MIC reached, and DMSO added as L...
ORGANISM(S): Staphylococcus Aureus 
PXD035364 |
ProteomicsGSK2018682 against Staphylococcus aureus proteome
Staphylococcus aureus (S, aureus) is common gram-positive bacteria that prominently causes community acquired infection (CAl) and hospital acquired infection (HAl) makes it a versatile and dangerous, Antibiotic resistance and the long - term nature of new drug research and development have forced th...
ORGANISM(S): Staphylococcus Aureus 
PXD066899 |
Proteomicsproteomic response of S. aureus with entrectinib treatment
S. aureus isolate was inoculated and cultured to exponential growth phase (OD600 at 0.5) in TSB and divided into two groups, the control group and the drug treated group. Entrectinib was added to the drug treated group until a final concentration of 1/2× MIC reached, and DMSO added in the control gr...
ORGANISM(S): Staphylococcus Aureus 
2022-11-23 | PXD038342 |
ProteomicsComparison of the significantly differentially expressed protein between K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB treated with 8% xylose
The K. pneumoniae K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB isolates were cultured overnight in MRS medium, then 1:200 diluted in MRS medium with 8% xylose to reach the exponential growth phase. The control group was K2044 treated with 8% xylose. The experiment was performed in triplicate.
ORGANISM(S): Klebsiella Pneumoniae 1191100241 
2024-11-04 | PXD057506 |
ProteomicsLactylation-stabilized NOL6 promotes colorectal cancer progression via recruiting STAMBP to deubiquitinate YY1 and upregulate MYC transcription
Colorectal cancer (CRC) represents a significant menace to human health, but its molecular pathogenesis remains unclear. Herein, we explored the functional role of Spindle and Nucleolar Protein 6 (NOL6) in CRC progression. In this study, we found NOL6 was significantly overexpressed in CRC tissues, ...
ORGANISM(S): Homo Sapiens 
PXD069802 |
ProteomicsHigh-resolution spatially resolved proteomics of complex tissues based on microfluidics and transfer learning
We develop a parallel flow projection and transfer learning-based spatial proteomics framework that combines microfluidics and a deep neutral network.
ORGANISM(S): Homo Sapiens Rattus Norvegicus Mus Musculus 
2025-01-15 | PXD045687 |
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