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ProteomicsHuman LMO2 binding protein LC-MSMS in U87MG(Glioblastoma cell)
To identify the binding partner of LMO2 for explanation of STAT3 signal-related protein in human glioblastoma
ORGANISM(S): Homo sapiens (Human) 
2022-08-11 | PXD028254 | Pride
Human Lmo2 Glioblastoma 
TranscriptomicsIdentification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma
LMO2 regulates gene expression facilitating the formation of multipartite DNA-binding complexes. In B cells, LMO2 is specifically up-regulated in the Germinal Center (GC) reaction and is expressed in GC-derived non-Hodgkin’s lymphomas. LMO2 is one of the most powerful prognostic indicators in DLBCL ...
ORGANISM(S): Homo sapiens 
2012-07-12 | E-GEOD-34576 | biostudies-arrayexpress
ProteomicsLMO2/LDB1 protein complex in AML cells
These are raw mass spectrometry data discussed in our paper: “The LMO2-LDB1-TAL1 complex regulates transcription networks in AML”, where we implicate this multisubunit complex as a key regulator of leukemia cell transcription. The key method was affinity purification followed by tandem mass spectrom...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD068576 | Pride
Complexes Immunoprecipitation Human 
TranscriptomicsTranscriptional profiling of mouse wild type Lmo2 transgenic DN thymocytes, and wild type bone marrow
Transcriptional profiling of Lmo2 transgenic DN thymocytes
ORGANISM(S): Mus musculus 
2010-01-22 | E-TABM-860 | biostudies-arrayexpress
GenomicsLmo2 is dispensable for maintenance of most Lmo2-induced murine T-cell leukemias
Lmo2 is dispensable for maintenance of most Lmo2-induced murine T-cell leukemias
PRJNA517144 | ENA
TranscriptomicsOverexpression of LMO2 causes aberrant human T-cell development in vivo by three potentially distinct cellular mechanisms
LMO2 overexpressing transgenic mouse models suggest an accumulation of immature T-cell progenitors in the thymus as main pre-leukemic event. The effects of LMO2 overexpression on human T-cell development in vivo, however, are unknown. Here we report studies of a humanized mouse model transplanted wi...
ORGANISM(S): Homo sapiens 
2016-03-26 | E-GEOD-79625 | biostudies-arrayexpress
UnknownA novel transcript of the LMO2 gene, LMO2-c, is regulated by GATA-1 and PU.1 and encodes an antagonist of LMO2.
Not available
S-EPMC2676384 | biostudies-literature
GenomicsLMO2 regulates epithelial-mesenchymal plasticity of mammary epithelial cells
LMO2 regulates epithelial-mesenchymal plasticity of mammary epithelial cells
PRJNA1271543 | ENA
UnknownCompetitive SPR using an intracellular anti-LMO2 antibody identifies novel LMO2-interacting compounds.
Not available
S-EPMC8208243 | biostudies-literature
TranscriptomicsLmo2 is dispensable for maintenance of most Lmo2-induced murine T-cell leukemias
Lmo2 is an oncogenic transcription factor that is a frequent target of chromosomal abnormalities in this T-cell acute lymphoblastic leukemia (T-ALL). In transgenic mouse models, overexpression of Lmo2 causes thymocyte self-renewal leading to T-cell leukemia with long latency. However, the requiremen...
ORGANISM(S): Mus musculus 
2022-01-01 | GSE125674 | GEO
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