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ProteomicsCell-specific analysis of tumour-endothelial contact-intiated signalling - PROTEOMICS
Metastasizing tumor cells exit the vascular system through dynamic interactions with endothelial cells that line the internal surface of vessels. While extravasation is a key event within the metastatic cascade, the signals regulating tumor cell adhesion to the endothelium and their subsequent trans...
ORGANISM(S): Homo sapiens (Human) 
2016-02-12 | PXD003048 | Pride
Epha2 Mda-mb-231-lm2 "contact-initiated signaling" Huvec 
ProteomicsCell-specific analysis of tumour-endothelial contact-intiated signalling
Tumour cell extravasation is a key event for metastatic colonisation1. However, little is known about the signalling pathways that govern tumour cell adhesion to the endothelium and subsequent transmigration through the blood vessel wall. Here, we combine Stable Isotope Labelling by Amino acids in C...
ORGANISM(S): Homo sapiens (Human) 
2016-02-12 | PXD001558 | Pride
Orbitrap velos Phospho Contact-initiated signalling Silac Transendothelial migration Mda-mb-231 Huvec 
ProteomicsDIA-PASEF acquisition of mixed-species samples for ProteoBench
Analysis of samples with peptides from different species in known amounts to compare performances of data analysis software tools within the ProteoBench platform.
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2025-05-09 | PXD062685 | Pride
Benchmarking  ground truth 
UnknownThe C-type lectin DCIR contributes to the immune response and pathogenesis of colorectal cancer.
Not available
S-EPMC10966077 | biostudies-literature
MetabolomicsMulti-omics characterization of acquired Olaparib resistance in BRCA1 and BRCA2 mutant breast cancer cell lines
Poly (ADP-ribose) polymerase inhibitors (PARPi) are widely used as targeted therapies against breast cancers with BRCA mutations. However, the development of resistance to PARPi poses a significant challenge for long-term efficacy of these therapies, warranting further understanding of mechanisms of...
2026-05-11 | MTBLS12109 | MetaboLights
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