Sort   by:  
 Page size 
TranscriptomicsSch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L (mRNA-Seq data)
TORC1 is a structurally and functionally conserved multiprotein complex that regulates many aspects of eukaryote growth including the synthesis and assembly of ribosomes. The protein kinase activity of this complex is responsive to environmental cues and is potently inhibited by the natural product ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-07-01 | E-GEOD-29122 | biostudies-arrayexpress
GenomicsSch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L (ChIP-Seq data)
TORC1 is a structurally and functionally conserved multiprotein complex that regulates many aspects of eukaryote growth including the synthesis and assembly of ribosomes. The protein kinase activity of this complex is responsive to environmental cues and is potently inhibited by the natural product ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-07-01 | E-GEOD-29124 | biostudies-arrayexpress
ProteomicsYeast AGC-kinases phospho-proteomics
Protein phosphorylation cascades play a central role in the regulation of cell growth and protein kinases PKA, Sch9 and Ypk1 take centre stage in regulating this process in S. cerevisiae. To understand how these kinases co-ordinately regulate cellular functions we compared the phospho-proteome of ex...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-02-27 | PXD015668 | Pride
Ypk1 Chemical genetics Agc-kinases Pka Sch9 S. cerevisiae 
ProteomicsPhosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55
Protein phosphatase regulatory subunits are increasingly recognized as promising drug targets. In the absence of an existing drug, inducible degradation provides a means of predicting candidate targets. We here employed auxin-inducible degradation of S. cerevisiae PP2A regulatory subunit Cdc55 in co...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-10-15 | PXD019481 | Pride
Degron Protein phosphatase Silac Pp2a Phosphoproteomics Lc-msms 
TranscriptomicsSch9 Is a Major Target of TORC1 in Saccharomyces cerevisiae
The Target Of Rapamycin (TOR) protein is a Ser/Thr kinase that functions in two distinct multiprotein complexes: TORC1 and TORC2. These conserved complexes regulate many different aspects of cell growth in response to intra- and extracellular cues. Here we report the first bona fide substrate of yea...
ORGANISM(S): Saccharomyces cerevisiae 
2010-09-15 | E-GEOD-7660 | biostudies-arrayexpress
ProteomicsCryoEM architecture of a near-native stretch-sensitive membrane microdomain
Eisosomes, stress-sensitive membrane compartments in yeast, are scaffolded by the BAR-domain proteins Pil1 and Lsp1. We isolated near-native eisosomes as helical filaments of Pil1/Lsp1 lattice bound to plasma membrane lipids and solved their structure by helical reconstruction. From the same near-na...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-07-18 | PXD050326 | Pride
Membrane microdomain Eisosome Pil1 Lsp1 
TranscriptomicsTranscription profiling of different strains of yeast exposed to arsenic stress
Effect of arsenic stress on cellular metabolism, respectively on transcription factors in the yeast Saccharomyces cerevisiae
ORGANISM(S): Saccharomyces cerevisiae 
2008-09-02 | E-MEXP-1075 | biostudies-arrayexpress
TranscriptomicsA Signaling Lipid Associated with Alzheimer’s Disease Promotes Mitochondrial Dysfunction
Fundamental changes in the composition and distribution of lipids within the brain are believed to contribute to the cognitive decline associated with Alzheimer’s disease (AD). The mechanisms by which these changes in lipid composition affect cellular function and ultimately cognition are not well...
ORGANISM(S): Saccharomyces cerevisiae 
2016-01-21 | E-GEOD-40814 | biostudies-arrayexpress
ProteomicsPhosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc55
Protein phosphatase regulatory subunits are increasingly recognized as promising drug targets. In the absence of an existing drug, inducible degradation provides a means of predicting candidate targets. We here employed auxin-inducible degradation of S. cerevisiae PP2A regulatory subunit Cdc55 in co...
ORGANISM(S): Saccharomyces Cerevisiae 
2021-01-27 | PXD019534 | panorama
TranscriptomicsTranscription profiling of yeast mutants to determine gene regulation by sterol and sphingolipid composition
determination of gene regulation by sterol and sphingolipid composition
ORGANISM(S): Saccharomyces cerevisiae 
2009-02-25 | E-TABM-544 | biostudies-arrayexpress
Sort   by:  
 Page size