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TranscriptomicsTranscription profiling of heart left ventricles from 15 week old inbred COP, DA, and F1(COP x DA) offspring with respect to aerobic running capacity (low, high, and intermediate performers respectively)
We used high density oligonucleotide arrays to measure the relative expression levels of ~27,000 probe sets in the left ventricles of inbred rat strains; DA (high performing), Copenhagen (COP, low performing), as well as F1(COPxDA) rats bred from these tw
ORGANISM(S): Rattus norvegicus 
2007-09-13 | E-GEOD-1795 | biostudies-arrayexpress
MetabolomicsMetabolomic Profiling of Submaximal Exercise at a Standardised Relative Intensity in Healthy Adults
Ten physically active subjects underwent two cycling exercise trials. In the first, aerobic capacity (VO2max) was determined and the second was a 45 min submaximal exercise test. Urine samples were collected separately the day before (day 1), the day of (day 2), and the day after (day 3) the submaxi...
2017-05-16 | MTBLS306 | MetaboLights
MetabolomicsDiel metabolomics analysis of a hot spring chlorophototrophic microbial mat leads to new hypotheses of community member metabolisms
Dynamic environmental factors such as light, nutrients, salt, and temperature continuously affect chlorophototrophic microbial mats, requiring adaptive and acclimative responses to stabilize composition and function. Quantitative metabolomics analysis can provide insights into metabolite dynamics fo...
2024-02-23 | MTBLS187 | MetaboLights
MetabolomicsTreatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics
Introduction: Obestatin is a controversial gastrointestinal peptide purported to have metabolic actions. Objectives: This study investigated whether treatment with a stable obestatin analogue (PEG-OB(Cys10, Cys13) changed plasma metabolite levels firstly in lean and subsequently in diet-induced obes...
2017-07-25 | MTBLS334 | MetaboLights
ProteomicsBONCAT enables time-resolved analysis of protein synthesis in native plant tissue
Pulsing the non-canonical amino acid azidohomoalanine into Arabidopsis thaliana seedlings enables in-gel visualization, physical enrichment, and identification of newly synthesized proteins.
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2017-07-03 | PXD005577 | JPOST Repository
ProteomicsiTRAQ-based proteomic analysis of dentate gyrus in temporal lobe epilepsy with hippocampal sclerosis
Temporal lobe epilepsy (TLE) is the most frequent type of focal epilepsy in adults, typically resistant to pharmacological treatment and mostly present with cognitive impairment and psychiatric comorbidities. The most common neuropathological hallmark in TLE patients is hippocampal sclerosis(HS). Ho...
ORGANISM(S): Homo sapiens (Human) 
2021-01-18 | PXD023048 | Pride
Temporal lobe epilepsy Dentate gyrus Quantitative proteomics Itraq Hippocampal sclerosis 
UnknownEvidence-Based Community Health Worker Program Addresses Unmet Social Needs And Generates Positive Return On Investment.
Not available
S-EPMC8564553 | biostudies-literature
TranscriptomicsAnalysis of postnatal gene expression in a transgenic rat kidney
We have generated a transgenic rat model with postnatal pathology. In order to investigate the potential contribution of changes in kidney gene expression to the pathology, we have conducted microarray-based gene expression profiling of postnatal kidney. Rat kidneys were sampled at mid-day of post...
ORGANISM(S): Rattus norvegicus 
2012-10-02 | E-GEOD-38595 | biostudies-arrayexpress
TranscriptomicsSost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner
WNT signaling is critical in most aspects of skeletal development and homeostasis, and antagonists of WNT signaling are emergning as key regulatory proteins with great promise as therapeutic agents for bone disorders. Until recently Sost and its paralog Sostdc1 have been described as growth factors ...
ORGANISM(S): Mus musculus 
2013-08-17 | E-GEOD-44325 | biostudies-arrayexpress
ProteomicsLong non-coding RNA Neat1 is a key of translational regulator in hypoxia
Internal ribosome entry sites (IRESs) drive translation initiation during stress. In response to hypoxia, (lymph)angiogenic factors responsible for tissue revascularization in ischemic diseases are induced by the IRES-dependent mechanism. Here we searched for IRES trans-acting factors (ITAFs) active...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-03 | PXD024067 | Pride
Nanolc-ms/ms Translational control Hypoxia Cardiomyocyte Label-free quantitative proteomics 
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