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UnknownA low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
Not available
S-EPMC6005420 | biostudies-literature
ProteomicsPrion-like low complexity regions enable avid virus-host interactions during HIV-1 infection
Cellular proteins CPSF6, NUP153 and SEC24C play crucial roles in HIV-1 infection. While weak interactions of short FG peptides to isolated capsid hexamers have been characterized, how these proteins engage biologically relevant extended HIV-1 capsid lattices is unknown. We have identified that prion...
ORGANISM(S): Homo sapiens (Human) Human immunodeficiency virus 
2022-08-31 | PXD030332 | Pride
Hdx-ms Cpsf6 Hiv-1 
UnknownAssessing the low complexity of protein sequences via the low complexity triangle.
Not available
S-EPMC7773278 | biostudies-literature
UnknownThe Disordered C-Terminus of Yeast Hsf1 Contains a Cryptic Low-Complexity Amyloidogenic Region.
Not available
S-EPMC5983738 | biostudies-literature
TranscriptomicsRibosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity of Mammalian Proteomes
The ability to sequence genomes has far outstripped approaches for deciphering the information they encode. Here we present a suite of techniques, based on ribosome profiling (the deep-sequencing of ribosome-protected mRNA fragments), to provide genome-wide maps of protein synthesis as well as a p...
ORGANISM(S): Mus musculus 
2011-11-03 | E-GEOD-30839 | biostudies-arrayexpress
UnknownLow Complexity Regions in Proteins and DNA are Poorly Correlated.
Not available
S-EPMC10124876 | biostudies-literature
TranscriptomicsLow input Hi-C datasets for a diffuse large B-cell lymphoma sample, healthy control human B-cells and mouse embryonic stem cells
In this experiment, we've examined chromatin conformation of OG2 (B6; CBA-Tg(Pou5f1-EGFP)2Mnn/J; stock number 004654) mouse stem cells cultured as described in (Shi et al., 2008), using different amounts of starting cells. We performed a modified in situ Hi-C protocol for 6 samples digested with Mbo...
ORGANISM(S): Mus musculus 
2018-11-30 | E-MTAB-5875 | biostudies-arrayexpress
TranscriptomicsRate of elongation by RNA polymerase II is influenced by specific gene features and histone modifications
The rate of transcription elongation plays important roles in the timing of expression of full-length transcripts as well as for the regulation of alternative splicing. In this study we coupled Bru-Seq technology with 5,6-dichlorobenzimidazole 1-M-NM-2-D-ribofuranoside (DRB) to estimate the elongati...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-55534 | biostudies-arrayexpress
UnknownA low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5'-3' messenger RNA decay.
Not available
S-EPMC6753473 | biostudies-literature
UnknownN6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein.
Not available
S-EPMC5449601 | biostudies-literature
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