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Tomosyn (STXBP5) is a non-canonical SNARE protein enriched in many secretory cells and implicated in regulation of exocytosis. In neurons, loss of tomosyn affects fusion of synaptic vesicles. Here, we examined the impact of the loss of tomosyn (STXBP5) and its close paralog, tomosyn-2 (STXBP5L), on ...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-19 | PXD038442 | Pride
Alcoholic hepatitis (AH) is the most severe form of alcoholic liver disease and occurs in patients with excessive alcohol intake It is characterized by marked hepatocellular damage, steatosis and pericellular fibrosis. Patients with severe AH have a poor short-term prognosis. Unfortunately, current ...
ORGANISM(S): Homo sapiens 
The acquisition of a proliferating cell status from a quiescent state as well as the shift between proliferation and differentiation are key developmental steps in skeletal-muscle stem cells (satellite cells) to provide proper muscle regeneration. However, how satellite-cell proliferation is regulat...
ORGANISM(S): Mus musculus 

Drought represents a major threat to food security. Mechanistic data describing plant responses to drought have been studied extensively and genes conferring drought resistance have been introduced into crop plants. However, plants with enhanced drought resistance usually display lower growth, hi...

2021-05-17 | MTBLS2289 | MetaboLights
we have conducted a comparative study of the different technologies available for the detection of chromosomal abnormalities in prenatal samples. Here we include results of the aCGH experiments this series is composed of internal controls plus a year-long (2009-2010) consecutive series of pregnant w...
ORGANISM(S): Homo sapiens 
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