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GenomicsTranscriptional profiling of LS1034 cells treated with tepoxalin
Transcriptional profiling of LS1034 cells treated with tepoxalin
PRJNA550993 | ENA
TranscriptomicsRNAseq of colorectal cancer cell lines (LS1034/HCT116) cultured with iPSC-derived intestinal stroma, separated by EpCAM expression (MACS). Monocultures of each cell line and co-cultures with LS1034 or HCT116 with stroma.
Colorectal cancer (CRC) cell lines (LS1034 and HCT116, representing different genetic backgrounds of CRC) were co-cultured with iPSC-derived intestinal stroma (described in other protocols). Control conditions were each cell line cultured separately. A dose response for HCT116 on stroma was tested u...
ORGANISM(S): Homo sapiens 
2026-03-02 | E-MTAB-13803 | biostudies-arrayexpress
GenomicsRNAseq of colorectal cancer cell lines (LS1034/HCT116) cultured with iPSC-derived intestinal stroma, separated by EpCAM expression (MACS). Monocultures of each cell line and co-cultures with LS1034 or HCT116 with stroma.
RNAseq of colorectal cancer cell lines (LS1034/HCT116) cultured with iPSC-derived intestinal stroma, separated by EpCAM expression (MACS). Monocultures of each cell line and co-cultures with LS1034 or HCT116 with stroma.
PRJEB72641 | ENA
TranscriptomicsA Gene Expression Signature for Chemoradiosensitivity of Colorectal Cancer Cells
In this study, we use cancer cell lines to investigate the molecular differences between resistant and responsive colorectal cancer cells. Since the treatment of patients with locally advanced rectal cancers involves chemoradiotherapy (CT/RT), we specifically implemented an in vitro protocol that m...
ORGANISM(S): Homo sapiens 
2011-02-10 | E-GEOD-20298 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of LS1034 cells treated with tepoxalin
LS1034 colorectal cancer cells were treated with DMSO vehicle control or 12 uM tepoxalin for 6 hours. Anti-cancer uses of non-oncology drugs have been found on occasion, but such discoveries have been serendipitous and rare. To fully discover activity against multiple tumor types, resource-intensive...
ORGANISM(S): Homo sapiens 
2019-08-08 | GSE133286 | GEO
ProteomicsInteractome of POU5F1B detected by LC-MSMS in HT29 and LS1034 CRC cells overexpressing POU5F1B-HA
The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor, we found that expression of the hominid-restricted retrogene POU5F1B...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD028034 | Pride
Human Lc-msms Pou5f1b Ht29 Ls1034 Overexpression Colorectal cancer 
ProteomicsSILAC & LC-MSMS in total cell extracts or in the secretome of sh-scramble vs. shRNA3 & shRNA5 LS1034 cells
The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor, we found that expression of the hominid-restricted retrogene POU5F1B...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD028036 | Pride
Human Knock-down Lc-msms Pou5f1b Ls1034 Silac Colorectal cancer 
UnknownMicroenvironmentally-driven Plasticity of CD44 isoform expression determines Engraftment and Stem-like Phenotype in CRC cell lines.
Not available
S-EPMC7359088 | biostudies-literature
UnknownKeratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cells.
Not available
S-EPMC3767798 | biostudies-literature
UnknownSynergistic Effects of the Combination of Alpelisib (PI3K Inhibitor) and Ribociclib (CDK4/6 Inhibitor) in Preclinical Colorectal Cancer Models.
Not available
S-EPMC11676898 | biostudies-literature
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