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ProteomicsInteractome of POU5F1B detected by LC-MSMS in HT29 and LS1034 CRC cells overexpressing POU5F1B-HA
The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor, we found that expression of the hominid-restricted retrogene POU5F1B...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD028034 | Pride
Human Lc-msms Pou5f1b Ht29 Ls1034 Overexpression Colorectal cancer 
ProteomicsSILAC & LC-MSMS in total cell extracts or in the secretome of POU5F1B- vs. GFP-overexpressing SW480 cells
The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor, we found that expression of the hominid-restricted retrogene POU5F1B...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD028035 | Pride
Human Lc-msms Pou5f1b Silac Overexpression Sw480 Colorectal cancer 
GenomicsTransposon-activated POU5F1B promotes colorectal cancer growth and metastasis III
Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis III
PRJNA756304 | ENA
GenomicsTransposon-activated POU5F1B promotes colorectal cancer growth and metastasis II
Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis II
PRJNA756305 | ENA
GenomicsTransposon-activated POU5F1B promotes colorectal cancer growth and metastasis I
Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis I
PRJNA675508 | ENA
UnknownWNK2 may promote ovarian cancer progression by upregulating POU5F1B.
Not available
S-EPMC12863568 | biostudies-literature
UnknownTransposon-activated POU5F1B promotes colorectal cancer growth and metastasis.
Not available
S-EPMC9392749 | biostudies-literature
TranscriptomicsTransposon-activated POU5F1B promotes colorectal cancer growth and metastasis III
The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor, we found that expression of the hominid-restricted retrogene POU5F1B...
ORGANISM(S): Homo sapiens 
2022-08-02 | GSE182466 | GEO
TranscriptomicsTransposon-activated POU5F1B promotes colorectal cancer growth and metastasis II
The treatment of colorectal cancer (CRC) is an unmet medical need in absence of early diagnosis. Here, upon characterizing cancer-specific transposable element-driven transpochimeric gene transcripts (TcGTs) produced by this tumor, we found that expression of the hominid-restricted retrogene POU5F1B...
ORGANISM(S): Homo sapiens 
2022-08-02 | GSE182465 | GEO
TranscriptomicsTransposon-activated POU5F1B promotes colorectal cancer growth and metastasis I
Tumors occasionally express oncogenes via aberrant activation of transposable elements (TE), but a role for this process in oncogenesis was seldom demonstrated. Here, we identify expression of the hominid-restricted retrogene POU5F1B through aberrant activation of an endogenous retroviral promoter a...
ORGANISM(S): Homo sapiens 
2022-08-02 | GSE161083 | GEO
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