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TranscriptomicsMicroRNA expression profiling in laryngeal squamous cell carcinoma (LSCC)
In this study, we aimed to explore the role of miR-145, which is downregulated in LSCC, on cancer stem cell potency of laryngeal cancer cells. Using microRNA expression profiling and experimental follow-up studies, we demonstrated the regulatory role of miR-145 in stem cell characteristics of Hep-2 ...
ORGANISM(S): Homo sapiens 
2015-11-10 | E-GEOD-70289 | biostudies-arrayexpress
ProteomicsProteomic Analysis of FSCN1-Interacting Proteins in LSCC cells
Fascin actin-bundling protein 1 (FSCN1) is an evolutionarily conserved actin-bundling protein that plays a critical role in cell migration, motility, adhesion and cellular interactions. Although multiple clinical studies have implicated the expression of FSCN1 in laryngeal squamous cell carcinoma (L...
ORGANISM(S): Homo sapiens (Human) 
2019-09-09 | PXD013072 | Pride
Lscc Ls-ms/ms Fscn1 Interactomics Immunoprecipitation 
TranscriptomicsRNA-seq of Tumor Initiating Cells (TICs) from Lung Squamous Cell Carcinoma (LSCC) lines reveals PRKCI dependent Hedgehog (HH) Signalling
RNA-seq analysis was performed on TICs and the parental counterparts of 4 LSCC cell lines. In addition, PRKCI knock down (KD) variants of these cells were sequenced. Subsequent analysis revealed that activation of HH signaling, a known driver of the TIC phenotype, is dependent on PRKCI expression. E...
ORGANISM(S): Homo sapiens 
2014-03-28 | E-GEOD-48599 | biostudies-arrayexpress
GenomicsScreening of differentially expressed genes in LSCC cells knocking down FSCN1
Screening of differentially expressed genes in LSCC cells knocking down FSCN1
PRJNA1073840 | ENA
TranscriptomicsSingle-cell RNA Sequencing (scRNA-seq) of Laryngeal Squamous Cell Carcinoma (LSCC) Tissues
Background: Laryngeal squamous cell carcinoma (LSCC) is a highly malignant tumor originated from respiratory system. Although there have been many improvements in therapy until now, reducing the high mortality is still difficult. Understanding the cellular heterogeneity of LSCC could contribute to i...
ORGANISM(S): Homo sapiens 
2020-05-12 | GSE150321 | GEO
GenomicsMicroRNA expression profiling in laryngeal squamous cell carcinoma (LSCC)
In this study, we aimed to explore the role of miR-145, which is downregulated in LSCC, on cancer stem cell potency of laryngeal cancer cells. Using microRNA expression profiling and experimental follow-up studies, we demonstrated the regulatory role of miR-145 in stem cell characteristics of Hep-2 ...
ORGANISM(S): Homo sapiens 
2015-11-10 | GSE70289 | GEO
UnknownCAF derived IL-33 mediated EMT to promote the metastasis of LSCC cells.
Not available
S-EPMC12636156 | biostudies-literature
UnknownLSCC SNP variant regulates SOX2 modulation of VDAC3.
Not available
S-EPMC5976468 | biostudies-literature
ProteomicsInfluence of Lactococcus cremoris and iodophor-based teat disinfectants on the cow milk proteome
In a recent study, a teat disinfectant based on a nisin-producing Lactococcus cremoris displayed comparable efficacy to a conventional iodophor disinfectant in preventing dairy cow mastitis when implemented in the dairy cow milking routine. Here, we carried out a longitudinal study for an in-depth i...
ORGANISM(S): Bos taurus (Bovine) 
2024-10-17 | PXD045030 | Pride
Proteomics  nanolc-ms/ms 
UnknowncircTUBD1-hnRNPK Regulates the Proliferation and Migration of LSCC by Targeting CCAR1.
Not available
S-EPMC11933862 | biostudies-literature
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