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ProteomicsIdentification of the proteins secreted by normal and cirrhotic LSECs
Normal and cirrhotic LSECs can influence hepatic stellate cells (HSCs) differently. This project aims to determine the set of proteins secreted by LSECs from healthy and cirrhotic livers, and identify the protein(s) that promote HSC activation.
ORGANISM(S): Mus musculus (Mouse) 
2018-11-06 | PXD009010 | Pride
Shotgun proteomics Ms Lsecs 
GenomicsGene signatures detect damaged LSECs in all chronic liver diseases.
Gene signatures detect damaged LSECs in all chronic liver diseases.
PRJNA748010 | ENA
UnknownLiver sinusoidal endothelial cells (LSECs) modifications in patients with chronic hepatitis C.
Not available
S-EPMC6584733 | biostudies-literature
GenomicsRNA-seq of primary murine liver sinusoidal endothelial cells (LSECs) with Gata4 deficiency
RNA-seq of primary murine liver sinusoidal endothelial cells (LSECs) with Gata4 deficiency
PRJNA1328707 | ENA
GenomicsLncRNA Airn alleviates liver fibrosis and maintains LSECs differentiation via the KLF2-eNOS-sGC pathway
LncRNA Airn alleviates liver fibrosis and maintains LSECs differentiation via the KLF2-eNOS-sGC pathway
PRJNA728676 | ENA
GenomicsGene Expression Analysis of NK cells after co-culture with Liver Sinusoidal Endothelial Cells (LSECs)
Gene Expression Analysis of NK cells after co-culture with Liver Sinusoidal Endothelial Cells (LSECs)
PRJNA975489 | ENA
TranscriptomicsTranscriptome of human liver cells and culture-activated hepatic stellate cells
The molecular determinants of a healthy human liver cell phenotype remain largely uncharacterized. In addition, the gene expression changes associated with activation of primary human hepatic stellate cells, a key event during fibrogenesis, remain poorly characterized. Here, we provide the transript...
ORGANISM(S): Homo sapiens 
2016-03-02 | E-GEOD-68000 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells
The human liver contains multiple cell types whose epigenetic patterns are undetermined. We examined the promoter methylome of purified and uncultured hepatic stellate cells (HSCs), hepatocytes (HEPs) and liver sinusoidal endothelial cells (LSECs), by methylated DNA immunoprecipitation (MeDIP) and a...
ORGANISM(S): Homo sapiens 
2015-12-21 | E-GEOD-66796 | biostudies-arrayexpress
UnknownThe role of microRNAs in defining LSECs cellular identity and in regulating F8 gene expression.
Not available
S-EPMC10910020 | biostudies-literature
TranscriptomicsRNA-seq of primary murine liver sinusoidal endothelial cells (LSECs) with Gata4 deficiency
Liver sinusoidal endothelial cells (LSECs) form discontinuous, permeable microvessels, with a unique gene expression program that differs significantly from that of continuous microvascular endothelial cells in other organs such as the lungs. Gata4 is one of the main transcription factors that drive...
ORGANISM(S): Mus musculus 
2026-09-29 | GSE308082 | GEO
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