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ProteomicsMCF7 treated with abemaciclib nuclear Rb IP LC-MSMS
The retinoblastoma protein (Rb) is a tumour suppressor best known for repressing E2F transcription factors and halting cell cycle progression1. In hormone receptor-positive (HR+) breast cancer, CDK4/6 inhibitors activate Rb by preventing its phosphorylation, forming a key component of current endocr...
ORGANISM(S): Homo sapiens (Human) 
2026-06-23 | PXD066496 | Pride
Rb Lc-msms Cdk4/6i Ip Breast cancer 
UnknownHamilton's inclusive fitness maintains heritable altruism polymorphism through rb = c.
Not available
S-EPMC5828573 | biostudies-literature
UnknownJMJD3 promotes SAHF formation in senescent WI38 cells by triggering an interplay between demethylation and phosphorylation of RB protein.
Not available
S-EPMC4563788 | biostudies-literature
ProteomicsProteome changes in larval zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) exposed anatoxin-a fumerate.
Characterization of proteome changes to zebrafish and fathead minnow following exposure to the Anatoxin-a surrogate anatoxin-fumerate.
ORGANISM(S): Pimephales Promelas (ncbitaxon:90988) Danio Rerio (ncbitaxon:7955) 
2023-11-29 | MSV000093536 | MassIVE
MetabolomicsDynamic utilization of low-molecular-weight organic substrates across a microbial growth rate gradient

AIM: Low-molecular-weight organic substances (LMWOSs) are at the nexus between micro-organisms, plant roots, detritus and the soil mineral matrix. The nominal oxidation state of carbon (NOSC) has been suggested as a potential parameter for modelling microbial uptake rates of LMWO...

2023-08-14 | MTBLS3558 | MetaboLights
MetabolomicsSerum metabolomic profiles identify ER-positive early breast cancer patients at increased risk of disease recurrence in a multicentre population

PURPOSE: Detecting signals of micrometastatic disease in early breast cancer (EBC) patients could improve risk stratification and allow better tailoring of adjuvant therapies. We have previously shown that postoperative serum metabolomic profiles are predictive of relapse in a si...

2017-03-02 | MTBLS424 | MetaboLights
UnknownSMC5 modulates BAT thermogenesis and energy expenditure via cell cycle arrest-induced RB accumulation
Not available
EMPIAR-13505 | biostudies-other
UnknownTargeting LxCxE Cleft Pocket of Retinoblastoma Protein in Immunosuppressive Macrophages Inhibits Ovarian Cancer Progression.
Not available
S-EPMC12532034 | biostudies-literature
UnknownDissecting the genetic determinants and biological associations between body mass index and female reproductive disorders based on genome-wide association study.
Not available
S-EPMC12076840 | biostudies-literature
UnknownAn integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles.
Not available
S-EPMC8204970 | biostudies-literature
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