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ProteomicsLegionella pneumophila effector LegK3 phosphorylates multiple caspases involved in apoptosis signaling
Legionella pneumophila effector Legk3 phosphorylates caspase3/7/9 under infection, transfection, or in vitro purification
ORGANISM(S): Homo Sapiens 
2024-07-20 | PXD054088 |
ProteomicsLegionella pneumophila effector LegK3 directly phosphorylates multiple caspases involved in apoptosis signaling, including Caspase-3, Caspase-7, and Caspase-9
Legionella pneumophila effector Legk3 phosphorylates caspase3/7/9 under infection, transfection, or in vitro purification condition
ORGANISM(S): Homo Sapiens 
2024-07-28 | PXD054358 |
ProteomicsShigella induces stress granule formation by ADP-riboxanation of the eIF3 complex
We utilized a large-scale proteomic profiling strategy to quantitatively measure ADP-riboxanation (and classical ADP-ribosylation) levels of host proteins upon introduction of bacterial effectors. Notably, we identified the eukaryotic translation initiation factor 3 (eIF3) complex as a novel target ...
ORGANISM(S): Homo Sapiens 
2024-01-18 | PXD048666 |
ProteomicsOviposition control genes and expression of functional interference in D.citri
The research on oviposition related genes is the focus of insect molecular biology. Some studies have gradually understood the mechanism of oviposition related genes, including oviposition-gland-related genes, oogenesis-related genes, oviposition-location-related genes, and genes related to ovulatio...
ORGANISM(S): Diaphorina Citri 
2020-11-04 | PXD022359 |
ProteomicsA prokaryotic E2 enzyme imitates the ubiquitin pathway to regulate the antiviral cGAS
The cyclic oligonucleotide-based anti-phage signalling system (CBASS) is a typeof innate prokaryotic immune system. Composed of a cyclic GMP-AMP synthase (cGAS) and CBASS-associated proteins, CBASS utilizes cyclic oligonucleotides to activate antiviral immunity. One major class of CBASS contains a h...
ORGANISM(S): Serratia Marcescens Lct-sm213 
2024-02-27 | PXD050178 |
ProteomicsSalmonella enterica Serovar Typhimurium transcriptional regulator STM0347 mediates Flagellar Phase Variation via Hin invertase
To elucidate the STM0347 regulon in S. Typhimurium, we performed a quantitative proteomic profiling of stm0347 deletion mutant, compared with its parental WT strain.
ORGANISM(S): Salmonella Enterica Subsp. Enterica Serovar Typhimurium Str. Sl1344 
2022-06-27 | PXD034943 |
ProteomicsComparative Analysis of Soybean Seed Proteome Based on Different Mass Spectrometry Acquisition Strategies
This study established a soybean seed proteome database and analyzed the raw mass spectrometry data of BoxCar and DIA on MaxQuant based on this database. Subsequently, the three mass spectrometry acquisition strategies, DDA, DIA and BoxCar, were compared for their depth of protein identification, da...
ORGANISM(S): Glycine Max 
2024-05-16 | PXD052278 |
ProteomicsThe global succinylation of SARS-CoV-2-infect host cells reveals potential drug targets
Here we show a quantitative mass spectrometry-based succinylproteomics analysis of SARS-CoV-2 infection in Caco-2 cells, revealing dramatic reshape of succinylation on host and viral proteins.
ORGANISM(S): Homo Sapiens 
2021-12-06 | PXD030197 |
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