Sort   by:  
 Page size 
TranscriptomicsThe human nuclear exosome targeting complex is loaded onto newly synthesized RNA to direct early ribonucleolysis
Individual-nucleotide resolution UV-crosslinking and immunoprecipitation (iCLIP) followed by high-throughput sequencing of RBM7-associated transcripts. Note: these data relate to Figure 1, 2, 3, 4, 5 and 6 in Lubas, Andersen et al., Cell Reports 2014 RBM7-associated transcripts
ORGANISM(S): Homo sapiens 
2014-12-03 | E-GEOD-63791 | biostudies-arrayexpress
ProteomicsThe lncRNA MIR31HG regulates the senescence associated secretory phenotype
Oncogene-induced senescence provides a barrier against malignant transformation. Senescent cells secrete pro-inflammatory cytokines, chemokines and growth factors collectively known as the senescence-associated secretory phenotype (SASP). Paradoxically, the SASP can also negatively impact the neighb...
ORGANISM(S): Homo sapiens (Human) 
2021-03-02 | PXD017475 | Pride
Lncrna senescence mir31hg ybx1 sasp braf 
ProteomicsSelective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites
The centrosome is the master orchestrator of mitotic spindle formation and chromosome segregation in animal cells. Centrosome abnormalities are frequently observed in cancer, but little is known of their origin and about pathways affecting centrosome homeostasis. Here we show that autophagy preserve...
ORGANISM(S): Homo sapiens (Human) 
2019-09-12 | PXD014829 | Pride
Centrosome Selective autophagy Centrosome fragmentation Gabarap Mitosis Cep131 Autophagy Centriolar satellites Pcm1 
ProteomicsEukaryotic translation initiation factor 5A regulates autophagy via translation of ATG3
Autophagy is an essential catabolic process responsible for recycling of intracellular material and preserving cellular fidelity. Key to the autophagy pathway is the ubiquitin-like conjugation system mediating lipidation of Atg8 proteins and their anchoring to autophagosomal membranes. While regulat...
ORGANISM(S): Homo sapiens (Human) 
2018-04-27 | PXD008874 | Pride
Newly synthesized proteins Lc-ms Eif5a 
Sort   by:  
 Page size