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ProteomicsPseudouridylation of tRNA-derived fragments steers translational control in stem cells
Pseudouridylation (Ψ) is the most abundant and widespread type of RNA epigenetic modification in living organisms; however, the biological role of Ψ remains poorly understood. Here, we show that a Ψ-driven posttranscriptional program steers translation control to impact stem cell commitment during e...
ORGANISM(S): Homo sapiens (Human) 
2018-04-11 | PXD008676 | Pride
Dimethyl labelling Trna Pseudouridylation 
TranscriptomicsInhibition of miR-9 regulates HuR and DICER1 and blocks Hodgkin Lymphoma tumor outgrowth
An Hodgkin Lymphoma cell line have been treated with an LNA inhibitor for miR-9 or with a scramble LNA to identify miR-9 regulated pathways that could be important for Hodgkin Lymphoma pathogenesis. L428 cells were transfected with a miR-9 LNA inhibitor or a scrambled LNA. Total RNA was harvested 9 ...
ORGANISM(S): Homo sapiens 
2012-05-01 | E-GEOD-27529 | biostudies-arrayexpress
UnknownThe impact of rifaximin on inflammation and metabolism in alcoholic hepatitis: A randomized clinical trial.
Not available
S-EPMC8920190 | biostudies-literature
UnknownInfarct quantification with cardiovascular magnetic resonance using "standard deviation from remote" is unreliable: validation in multi-centre multi-vendor data.
Not available
S-EPMC9639305 | biostudies-literature
UnknownMeasuring extracellular volume fraction by MRI: First verification of values given by clinical sequences.
Not available
S-EPMC6900009 | biostudies-literature
UnknownImpact of COX2 genotype, ER status and body constitution on risk of early events in different treatment groups of breast cancer patients.
Not available
S-EPMC4225481 | biostudies-literature
ProteomicsSelective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites
The centrosome is the master orchestrator of mitotic spindle formation and chromosome segregation in animal cells. Centrosome abnormalities are frequently observed in cancer, but little is known of their origin and about pathways affecting centrosome homeostasis. Here we show that autophagy preserve...
ORGANISM(S): Homo sapiens (Human) 
2019-09-12 | PXD014829 | Pride
Centrosome Selective autophagy Centrosome fragmentation Gabarap Mitosis Cep131 Autophagy Centriolar satellites Pcm1 
UnknownIndependent validation of metric optimized gating for fetal cardiovascular phase-contrast flow imaging.
Not available
S-EPMC6282515 | biostudies-literature
TranscriptomicsPrdm5 suppresses ApcMin-driven intestinal adenomas and regulates monoacylglycerol lipase expression
PRDM proteins are tissue specific transcription factors often deregulated in diseases, particularly in cancer where different members have been found to act as oncogenes or tumor suppressors. PRDM5 is a poorly characterized member of the PRDM family for which several studies have reported a high fre...
ORGANISM(S): Mus musculus 
2013-05-11 | E-GEOD-46821 | biostudies-arrayexpress
UnknownTranscriptome dynamics of the microRNA inhibition response.
Not available
S-EPMC4513874 | biostudies-literature
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