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ProteomicsHuman plasma proteomics analysis of PAD patients and Healthy control
Blood samples from healthy controls and PAD patients were collected at Xiangya Hospital, China. Two to three milliliters of venous blood were drawn into EDTA-coated tubes and stored at 4°C. Plasma was isolated after centrifugation (2,000 g, 10 min, 4°C), aliquoted, and send to perform MS. Group1: He...
ORGANISM(S): Homo sapiens (Human) 
2025-10-07 | PXD056710 | Pride
Plasma proteomics 
ProteomicsMyeloid-derived grancalcin instigates obesity-induced insulin resistance and metabolic inflammation
The crosstalk between the bone and adipose tissue orchestrates the metabolic homeostasis, but the underlying mechanisms are largely unknown. Herein, we find that GCA+(grancalcin) immune cells accumulate in the bone marrow and release a sufficient amount of GCA into circulation during obesity. Geneti...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-06 | PXD045836 | Pride
Grancalcin  insulin resistance  metabolic inflammation 
UnknownA Poliovirus Receptor (CD155)-Related Risk Signature Predicts the Prognosis of Bladder Cancer.
Not available
S-EPMC8210672 | biostudies-literature
ProteomicsQuantitative Proteomics Reveals the Dynamic Pathophysiology across Different Stages in a Rat Model of Severe Traumatic Brain Injury
Background: Severe Traumatic Brain Injury (TBI) has become a growing health problem, causing a vast society burden worldwide. However, characteristic mechanisms between acute and subacute stages have not been systemically revealed. Methods: Sixty rats were randomly divided into sham surgery and mode...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-06-07 | PXD029312 | Pride
Acute phase Severe traumatic brain injury Subacute phase Characteristic mechanisms Quantitative proteomic Tandem mass tag-based 
ProteomicsLiquid chromatography-tandem mass spectrometry analysis of bone marrow from the ground or running rats
Exercise can prevent osteoporosis and improve immune function, but the mechanism remains unclear. To explore the key factors involved in these two processes, we collected bone marrow from ground and running rats and then conducted liquid chromatography-tandem mass spectrometry.
ORGANISM(S): Rattus norvegicus (Rat) 
2023-10-17 | PXD033807 | Pride
Fat metabolism Exercise Immunity Bone marrow fat Bone metabolism Lipolysis 
UnknownClinical outcomes following preimplantation genetic testing and microdissecting junction region in couples with balanced chromosome rearrangement.
Not available
S-EPMC7910386 | biostudies-literature
UnknownEpigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid.
Not available
S-EPMC6894084 | biostudies-literature
ProteomicsYBX1-IP in mouse bone marrw myeloma cells
The total protein of bone marrw myeloma cells was extracted with cell lysis buffer for IP. YBX1 antibody was used to perform Immunoprecipitation.
ORGANISM(S): Mus musculus (Mouse) 
2023-04-19 | PXD039386 | Pride
Bmscs Ybx1-ip 
UnknownJingzhaotoxin-X, a gating modifier of Kv4.2 and Kv4.3 potassium channels purified from the venom of the Chinese tarantula Chilobrachys jingzhao.
Not available
S-EPMC7269146 | biostudies-literature
ProteomicsMouse serum DIA-based proteomic profiling after 1-day or 7-day daily heat stress exposure
This project profiles heat stress (HS)-induced alterations in the mouse serum proteome to identify circulating proteins that are consistently regulated by HS. Mice were assigned to three groups: PF (pair-fed control at room temperature, RT), HS1D (daily HS for 1 day, 6 h/day), and HS7D (daily HS for...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-28 | PXD074893 | Pride
Mouse serum  dia proteomics 
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