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The integration of omics technologies into molecular biological research has transformed it into a field where a system can be investigated as a whole by combining information from multiple biochemical layers. This extension of traditional molecular biology, where various data sources are conside...

2025-11-12 | MTBLS12307 | MetaboLights

The central nervous system has been implicated in the age-induced reduction in adipose tissue lipolysis. SLC7A14 is a lysosomal membrane protein highly expressed in the brain. Herein, we investigated the possible role of hypothalamic SLC7A14 in the age-induced lipolysis reduction. In this study, ...

2024-07-23 | MTBLS9872 | MetaboLights
The unfolded protein response (UPR), induced by endoplasmic reticulum (ER) stress, regulates the expression of factors that restore protein folding homeostasis. However, in the liver and kidney, ER stress also leads to lipid accumulation, accompanied at least in the liver by transcriptional suppress...
2017-06-23 | MTBLS472 | MetaboLights
Not available
ORGANISM(S): Caenorhabditis elegans 
OBJECTIVE: Acromegaly is a rare endocrine disorder with excess growth hormone (GH) production. This disorder has important metabolic effects in insulin resistance and lipolysis. The objective of this study was to explore transcriptional changes induced by GH in adipose tissue. METHODS: The patients ...
ORGANISM(S): Homo sapiens 
The integration of omics technologies into molecular biological research has transformed it into a field where a system can be investigated as a whole by combining information from multiple biochemical layers. This extension of traditional molecular biology, where various data sources are considered...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-22 | PXD061570 | Pride
Endotoxin stimulates lipolysis in bovine adipocytes
Lipolysis regulates major transcriptional programs in brown adipocytes
Transcriptional regulation of adipocyte lipolysis by IRF2BP2 [RNA-seq]
Transcriptional regulation of adipocyte lipolysis by IRF2BP2 [CUT&RUN]
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