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ProteomicsMetabolic Reprogramming Driven by Ant2 Deficiency Augments T Cell Function and Anti-Tumor Immunity
cell activation demands a significant boost in NAD+ levels, often outpacing the capacity of oxidative phosphorylation (OXPHOS). To explore how T cells manage this metabolic stress, we created T cell-specific ADP/ATP translocase-2 knockout (Ant2-/-) mice. Ant2, which is vital for ADP/ATP exchange bet...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-09 | PXD062646 | Pride
Naive t cells Mouse Ant2ko Spleen 
UnknownChildhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study.
Not available
S-EPMC6206739 | biostudies-literature
UnknownLobar Emphysema Distribution Is Associated With 5-Year Radiological Disease Progression.
Not available
S-EPMC6026264 | biostudies-literature
UnknownPrevalence of abnormal spirometry in individuals with a smoking history and no known obstructive lung disease.
Not available
S-EPMC9990311 | biostudies-literature
UnknownWhole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification.
Not available
S-EPMC11138106 | biostudies-literature
UnknownA genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease.
Not available
S-EPMC4848212 | biostudies-literature
UnknownLung tissue shows divergent gene expression between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.
Not available
S-EPMC9026726 | biostudies-literature
GenomicsAlzheimer's Disease Sequencing Project (ADSP)

The overarching goals of the ADSP are to: (1) identify new genomic variants contributing to increased risk of developing AD, (2) identify new genomic variants contributing to protection against developing AD, and (3) provide insight as to why individuals with known risk factor variants escape fro...

phs000572.v1.p1 | EGA
UnknownGenome-wide association study and functional validation implicates JADE1 in tauopathy.
Not available
S-EPMC8786260 | biostudies-literature
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