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TranscriptomicsCombined miRNA and mRNA Sequencing Identifies Protective Transcriptional Signature of Enhanced PI3Kalpha Signaling in Cardiac Hypertrophy
A molecular and bioinformatic pipeline permitting comprehensive analysis and quantification of myocardial miRNA and mRNA expression with next-generation sequencing was developed and the impact of enhanced PI3Kalpha signaling on the myocardial transcriptome signature of pressure overload-induced path...
ORGANISM(S): Mus musculus 
2013-05-01 | E-GEOD-35350 | biostudies-arrayexpress
TranscriptomicsDeep RNA Sequencing Reveals Dynamic Regulation of Myocardial Noncoding RNA in Failing Human Heart and Remodeling with Mechanical Circulatory Support
Complete transcriptome profiling in human failing and non-failing control hearts using next-gen sequencing Poly-A selected RNA and small RNA sequencing carried out in 5 groups of samples: NF, ICM, NICM, ICM+LVAD, NICM+LVAD
ORGANISM(S): Homo sapiens 
2014-02-10 | E-GEOD-46224 | biostudies-arrayexpress
UnknownHeart deformation analysis: measuring regional myocardial velocity with MR imaging.
Not available
S-EPMC4958501 | biostudies-literature
UnknownNature of the liver volume depending on the gender and age assessing volumetry from a reconstruction of the computed tomography.
Not available
S-EPMC8654223 | biostudies-literature
UnknownThe impact of intravenous iron supplementation in elderly patients undergoing major surgery.
Not available
S-EPMC8988356 | biostudies-literature
UnknownChinese leek-derived extracellular vesicles ameliorate sarcopenia by regulating mitochondrial biogenesis and autophagy via AMPK and maintaining myosin homeostasis.
Not available
S-EPMC12632053 | biostudies-literature
ProteomicsMechanism of BceAB-type transporter: Resistance by lipid II flipping
Treatment of bacterial infections are the great challenge of our era due to the evolved resistance mechanisms against antibiotics. The Achilles heel of bacteria is the cell wall especially during the needs of its synthesis and cell division. Here lipid II is an essential precursor component synthesi...
ORGANISM(S): Bacteria Lactococcus lactis subsp. cremoris NZ9000 
2022-04-04 | PXD017318 | Pride
Bceab-type Bacitracin Nisin Antibiotic resistance Lipid ii 
TranscriptomicsRNA-seq of retinal organoids derived from RPGR patient-, control- and mutation-corrected-iPSC at different developmental stages
Retinitis pigmentosa (RP) is an irreversible and inherited retinopathy. RPGR mutations are the most common causes of this disease. It remains challenging to decipher the mechanism of RPGR mutation because of the lack of appropriate study models. The substitution of patient-specific diseased retina w...
ORGANISM(S): Homo sapiens 
2020-02-01 | E-MTAB-6490 | biostudies-arrayexpress
ProteomicsSolid diet improved rumen epithelial proteomics
This project investigated rumen proteomics affected by solid.
ORGANISM(S): Goat Adenovirus 1 
2023-12-14 | PXD047843 |
ProteomicsComprehensive genome editing and signaling pathway engineering evolve potent and safe adenoviral producer cell
Dramatic attention has been drawn to adenovirus as a vehicle for vaccine and cancer therapy, due to the capabilities of annihilating tumor cells and stimulating host immune response. However, few producer cells are perfect for adenoviral manufacture. Herein, a novel genome editing strategy by CRISPR...
ORGANISM(S): Homo Sapiens 
2025-10-21 | PXD069719 |
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