Sort   by:  
 Page size 
ProteomicsLysine trimethylation in planktonic and pellicle modes of growth in Acinetobacter baumannii
An increasing number of studies have shown the importance of post-translational modifications (PTM) in bacterial physiology, especially during biofilm formation. Trimethylation of lysine residues is little studied due to lack of specific enrichment methods for this PTM. However, it may have a signif...
ORGANISM(S): Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377) 
2023-07-20 | PXD035239 | Pride
Acinetobacter baumannii Planktonic Lysine trimethylation Proteomics Pellicle 
ProteomicsQuantitative histone mass spectrometry identifies elevated histone H3 lysine 27 trimethylation in melanoma
Normal cell growth is characterized by a regulated epigenetic program that drives cellular activities such as gene transcription, DNA replication and DNA damage repair. Perturbation of this epigenetic program can lead to events such as mis-regulation of gene transcription and diseases such as cancer...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079979 | MassIVE
GenomicsA histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing
BS69 (aka ZMYND11) was initially discovered as a direct target of adenoviral E1A oncoprotein1. Subsequent studies implicated BS69 as a tumor suppressor and a transcriptional regulator2. But exactly how BS69 regulates gene expression has remained elusive. BS69 contains tandemly arranged PHD, BROMO an...
ORGANISM(S): Homo sapiens 
2014-09-03 | E-GEOD-51672 | biostudies-arrayexpress
TranscriptomicsA histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing
BS69 (aka ZMYND11) was initially discovered as a direct target of adenoviral E1A oncoprotein1. Subsequent studies implicated BS69 as a tumor suppressor and a transcriptional regulator2. But exactly how BS69 regulates gene expression has remained elusive. BS69 contains tandemly arranged PHD, BROMO an...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-51261 | biostudies-arrayexpress
TranscriptomicsTranscriptomic regulation and methylation of the Lysine4 of Histone H3 during meiosis
This SuperSeries is composed of the following subset Series: GSE10836: Meiotic time course of Histone H3 occupancy GSE10837: Meiotic time course of the trimethylation of the Lysine 4 of Histone H3 (H3K4me3) in a mutant Spo11F GSE10838: Meiotic time course of Histone H3 occupancy in a mutant Spo11F G...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-31 | E-GEOD-11004 | biostudies-arrayexpress
GenomicsContext Dependency of Set1/COMPASS Mediated H3 Lysine 4 Trimethylation
The stimulation of trimethylation of histone H3 lysine 4 (H3K4) by H2B monoubiquitination (H2Bub) has been widely studied with multiple mechanisms proposed for this form of histone crosstalk. Cps35/Swd2 within COMPASS is considered to bridge these processes. However, a truncated form of Set1 (762-Se...
ORGANISM(S): Saccharomyces cerevisiae 
2014-01-09 | E-GEOD-53241 | biostudies-arrayexpress
ProteomicsQuantitative histone mass spectrometry identifies elevated histone H3 lysine 27 trimethylation in melanoma
Normal cell growth is characterized by a regulated epigenetic program that drives cellular activities such as gene transcription, DNA replication and DNA damage repair. Perturbation of this epigenetic program can lead to events such as mis-regulation of gene transcription and diseases such as cancer...
ORGANISM(S): Homo sapiens (Human) 
2015-12-02 | PXD002471 | Pride
Human Runx3 Histone h3 lysine 27 trimethylation Melanoma Ezh2 
TranscriptomicsStudy the histone H3 lysine 9 trimethylation (H3K9me3) in adenoid cystic carcinoma cell lines (ACC) via ChIP-chip by array
Chromatin immunoprecipitation on microarrays (ChIP-chip) has been widely used to investigate the DNA binding sites for a variety of proteins such as histone and transcription factors on a genome-wide scale. The purpose of this study is to evaluate the status of histone H3 lysine 9 trimethylation in ...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-MTAB-3053 | biostudies-arrayexpress
TranscriptomicsChIP-chip with antibodies for histone 3 lysine 4 trimethylation, histone 3, and PolII in Mll1+/+ and Mll1-/- MEFs
Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II A common landmark of activated genes is the presence of trimethylation on lysine 4 of histone H3 (H3K4) ...
ORGANISM(S): Mus musculus 
2010-06-21 | E-GEOD-18264 | biostudies-arrayexpress
TranscriptomicsHistone H3 lysine 27 trimethylation of miRNA genes in HMEC and HMF
Normal cell type specific histone H3 lysine 27 trimethylation of miRNA genes. HMEC and HMF represent two distinct differentiated cell type present in mammary gland each with a distinct phenotype, a distinct epigenotype as well as distinct miRNA expression pattern. The aim of the study was to determi...
ORGANISM(S): Homo sapiens 
2011-04-05 | E-GEOD-28376 | biostudies-arrayexpress
Sort   by:  
 Page size