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ProteomicsLysyl Oxidases are Necessary for Myometrial Contractility and On-Time Parturition in Mice
The extracellular matrix (ECM) plays a pivotal role in the maintenance of tissue mechanical homeostasis. Collagens and elastic fibers are the most predominant fibrous ECM proteins providing tissue mechanical function through covalent cross-linking, which is mediated by the lysyl oxidase family of en...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-18 | PXD055537 | Pride
Lysyl oxidase Pregnancy Extracellular matrix Myometrium Parturition 
GenomicsTopical application of an irreversible small molecule inhibitor of Lysyl Oxidases ameliorates skin scarring and fibrosis
Topical application of an irreversible small molecule inhibitor of Lysyl Oxidases ameliorates skin scarring and fibrosis
PRJNA685738 | ENA
UnknownFibrosis in Mesothelioma: Potential Role of Lysyl Oxidases.
Not available
S-EPMC8870010 | biostudies-literature
UnknownEssential role of lysyl oxidases in notochord development.
Not available
S-EPMC2467443 | biostudies-literature
UnknownInhibition of Lysyl Oxidases Improves Drug Diffusion and Increases Efficacy of Cytotoxic Treatment in 3D Tumor Models.
Not available
S-EPMC4665164 | biostudies-literature
UnknownTopical application of an irreversible small molecule inhibitor of lysyl oxidases ameliorates skin scarring and fibrosis.
Not available
S-EPMC9500072 | biostudies-literature
UnknownInteractions between lysyl oxidases and ADAMTS proteins suggest a novel crosstalk between two extracellular matrix families.
Not available
S-EPMC6240406 | biostudies-literature
UnknownOrigin and evolution of lysyl oxidases.
Not available
S-EPMC4448552 | biostudies-literature
ProteomicsSmall molecule inhibitors of lysyl oxidases synergize with 5-azacytidine to restore erythropoiesis in myeloid neoplasms
In this study, we assessed the effects of lysyl oxidase (LOX/LOXL) inhibition on the composition of extracellular matrix (ECM) produced by in vitro expanded bone marrow derived mesenchymal stromal cells (MSCs) of n=3 patients with myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN...
ORGANISM(S): Homo sapiens (Human) 
2023-02-17 | PXD031217 | Pride
Msc Lc-ms Human Ecm 
UnknownThe lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1.
Not available
S-EPMC2825461 | biostudies-literature
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