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ORGANISM(S): Homo sapiens 

Hyperuricemia (HUA) is a metabolic disorder marked by increased blood uric acid (UA) levels, closely linked to conditions such as gout. UA-induced macrophage M1 polarization fundamentally exacerbates inflammatory pathophysiology, but current HUA-specific immunoregulatory treatments are inadequat...

2026-01-26 | MTBLS13224 | MetaboLights
Human respiratory syncytial virus (RSV) is a globally prevalent negative-stranded RNA virus, which can cause life-threatening respiratory infections in young children, elderly people and immunocompromised patients. Its transcription termination factor M2-1 plays an essential role in viral transcript...
ORGANISM(S): Homo sapiens (Human) 
2019-10-11 | PXD013761 | Pride
Agrobacterium pusense M2/1 Genome sequencing
Limnobaculum sp. M2-1 Genome sequencing and assembly
Lysobacter sp. M2-1 Genome sequencing and assembly
Macrophages are effector cells of the innate immune system and undergo phenotypical changes in response to organ injury and repair. They are most often classified as proinflammatory M1 and anti-inflammatory M2 macrophages. Protein arginine deiminase (PAD) enzymes, that catalyze the conversion of pr...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD034591 | Pride
Proteomic alterations in OECM-1 cells induced by THP-1-derived M2 macrophage co-culture
ORGANISM(S): Homo Sapiens (human) 
This dataset comprises label-free quantitative proteomics of the secretome from human THP-1 serglycin (SRGN) knock-out and wild-type macrophage-like cells differentiated with PMA (M0) and polarized to M1 (LPS + IFN-γ) or M2 (IL-4 + IL-13). The study investigates how macrophage activation states in t...
ORGANISM(S): Homo sapiens (Human) 
2026-02-25 | PXD071481 | Pride
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