Sort   by:  
 Page size 
GenomicsNucleotide resolution profiling of m3C RNA modification by HAC-seq
Nucleotide resolution profiling of m3C RNA modification by HAC-seq
PRJNA662378 | ENA
UnknownM3C: Monte Carlo reference-based consensus clustering.
Not available
S-EPMC7000518 | biostudies-literature
UnknownNucleotide resolution profiling of m3C RNA modification by HAC-seq.
Not available
S-EPMC7969016 | biostudies-literature
OtherNucleotide resolution profiling of m3C RNA modification by HAC-seq
We report a m3C-specific high-throughput sequencing techinque, Hydrazine-Aniline Cleavage sequencing (HAC-seq) to profile the m3C methylome at single-nucleotide resolution. We apply HAC-seq to analyze ribosomal RNA-depleted total RNA from MCF7 cells. We find that tRNA are the predominant m3C-modifie...
ORGANISM(S): Homo sapiens 
2020-11-20 | GSE157682 | GEO
GenomicsSequencing of polyA+ RNA from shCtrl and shMETTL8 HeLa for m3C site identification
Sequencing of polyA+ RNA from shCtrl and shMETTL8 HeLa for m3C site identification
PRJNA1122093 | ENA
TranscriptomicsSequencing of polyA+ RNA from shCtrl and shMETTL8 HeLa for m3C site identification
N3-methylcytidine (m3C), an RNA modification involving methylation of cytidine at the Watson-Crick face, has been identified in human tRNA, mitochondrial tRNA (mt-tRNA), and mRNA. In tRNA, it has been shown to play important roles in tRNA structure and translation. m3C remains understudied in mRNA d...
ORGANISM(S): Homo sapiens 
2026-07-17 | GSE269470 | GEO
ProteomicsMETTL8 is required for 3-methylcytosine modification in human mitochondrial tRNAs
A subset of eukaryotic tRNAs is methylated in the anticodon loop to form the 3-methylcytosine (m3C) modification. In mammals, the number of tRNAs containing m3C has expanded to include mitochondrial (mt) tRNA-Ser-UGA and mt-tRNA-Thr-UGU. Whereas the enzymes catalyzing m3C formation in nuclear-encode...
ORGANISM(S): Homo sapiens (Human) 
2022-05-19 | PXD030418 | Pride
Trna modification 3-methylcytosine Trna Mitochondria Mettl8 M3c 
UnknownThe SUMOylated METTL8 Induces R-loop and Tumorigenesis via m3C.
Not available
S-EPMC7082549 | biostudies-literature
UnknownImplications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Not available
S-EPMC3744880 | biostudies-literature
GenomicsMETTL6 is a tRNA m3C methyltransferase that regulates translation and cell proliferation
METTL6 is a tRNA m3C methyltransferase that regulates translation and cell proliferation
PRJNA605175 | ENA
Sort   by:  
 Page size