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TranscriptomicsTranscriptomic analysis of grape (Vitis vinifera L.) leaves exposed to ultraviolet C radiation
Solar ultraviolet C（UV-C）radiation reaching the Earth’s surface is little due to the filtering effects of the stratospheric ozone layer. At present, artificial UV-C irradiation is utilized for different biological processes. Grape is a major fruit crop around the world. Research has shown that UV-C ...
ORGANISM(S): Vitis vinifera 
2014-11-15 | E-GEOD-62315 | biostudies-arrayexpress
TranscriptomicsMulticilin drives centriole biogenesis via E2f proteins
Biochemistry suggests e2f4 forms a complex with the coiled-coiled protein multicilin (MCIDAS), a protein that is necessary and sufficient to specify multiciliated cells in vertebrates. Here, we performed RNAseq on Xenopus laevis ectoderm in the presence of multicilin alone or multicilin and a domina...
ORGANISM(S): Xenopus laevis 
2014-07-10 | E-GEOD-59309 | biostudies-arrayexpress
MetabolomicsIAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function
The islet in type 2 diabetes (T2D) is characterized by amyloid deposits derived from islet amyloid polypeptide (IAPP), a protein co-expressed with insulin by β-cells. In common with amyloidogenic proteins implicated in neurodegeneration, human IAPP (hIAPP) forms membrane permeant toxic oligomers imp...
2020-04-17 | MTBLS951 | MetaboLights
TranscriptomicsGenome-wide analysis of microRNA expression in Non-small Cell Lung Cancer
Analysis of NSCLC development at microRNA expression level. Results shows that has-miR-96 is significant up-regulated in the cancer tissue compared with the adjacent normal tissue. Illumina Human v2 MicroRNA expression beadchip Total microRNA obtained from 6 paired NSCLC cancer tissue and the adjac...
ORGANISM(S): Homo sapiens 
2012-09-16 | E-GEOD-29248 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression in Non-small Cell Lung Cancer
Analysis of NSCLC development at gene expression level. Results shows that obvious activation of cell cycle pathway, and significant repression of cell-cell communication pathways. Illumina HumanHT-12 V4.0 expression beadchip Total RNA obtained from 6 paired NSCLC cancer tissue and the adjacent nor...
ORGANISM(S): Homo sapiens 
2012-09-16 | E-GEOD-29249 | biostudies-arrayexpress
TranscriptomicsAn Integrated Analysis of miRNA and mRNA Expressions of Non-small Cell Lung Cancer
This SuperSeries is composed of the following subset Series: GSE29248: Genome-wide analysis of microRNA expression in Non-small Cell Lung Cancer GSE29249: Genome-wide analysis of gene expression in Non-small Cell Lung Cancer Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-09-16 | E-GEOD-29250 | biostudies-arrayexpress
TranscriptomicsA RNA-seq-based gene expression profiling of radiation-induced tumorigenic mammary epithelial cells
To understand tumorigenesis and cancer progression of mammary epithelium, we established a cell model combining over-expression of human telomerase reverse transcriptase gene (hTERT) and heavy-ion radiation from normal human mammary epithelial cells. We subsequently used RNA-seq method to acquire th...
ORGANISM(S): Homo sapiens 
2013-12-09 | E-GEOD-31310 | biostudies-arrayexpress
TranscriptomicsNA-Seq reveals dynamic changes of gene expression in key stages of intestine regeneration in the sea cucumber Apostichopus japonicus.
Sea cucumbers (Holothuroidea; Echinodermata) have the capacity to regenerate lost tissues and organs.We used RNA-Seq to determine gene expression profiles associated with intestinal regeneration in A. japonicus at 3, 7, 14 and 21 days post evisceration (dpe) At least 15 individuals per stage, at 3,...
ORGANISM(S): Apostichopus japonicus 
2015-01-01 | E-GEOD-44995 | biostudies-arrayexpress
UnknownDevelopment of the Clinical pHysical rEsilience assEssment Scale (CHEES) in Chinese Older Adults.
Not available
S-EPMC12275678 | biostudies-literature
TranscriptomicsGlobal hepatic gene expression in rainbow trout exposed to sewage effluents
Effluents from sewage treatment plants contain a mixture of micropollutants with the potential of harming aquatic organisms. Thus, addition of advanced treatment techniques to complement existing conventional methods has been proposed. Some of the advanced techniques could, however, potentially prod...
ORGANISM(S): Oncorhynchus mykiss 
2012-05-09 | E-GEOD-37574 | biostudies-arrayexpress
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