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In the related study, to determine whether DUSP2 definitively served as a phosphatase for STAT3, an in vitro phosphatase assay was used. Using S-tag beads, p-STAT3 was pulled down from IL-6 stimulated HEK293T cells transfected with STAT3-S-Tag. DUSP2 or control protein, which was purified from HEK29...
ORGANISM(S): Homo sapiens (Human) 
2015-10-13 | PXD002743 | Pride
Type III adenylyl cyclase (AC3, ADCY3) is predominantly enriched in neuronal primary cilia throughout the central nervous system (CNS). Genome-wide association studies in humans have associated ADCY3 with major depressive disorder and autistic spectrum disorder, both of which exhibit sexual dimorphi...
ORGANISM(S): Mus musculus (Mouse) 
2019-04-10 | PXD012259 | Pride
To examine the molecular mechanisms by which PAC1 suppresses T cell response to antigen, we conducted immunoprecipitation followed by mass spectrometry to characterize PAC1-associated proteins in activated T cells
ORGANISM(S): Homo sapiens (Human) 
2020-01-07 | PXD012201 | Pride
Organic acid secretion is a widespread physiological response of plants to alkalinity. However, the features of alkali-induced secretion of organic acid and the underlying mechanism are poorly understood. Herein, it was indicated that oxalate was the main organic acid synthesized and secreted in vin...
ORGANISM(S): Vitis vinifera (Grape) 
2019-11-11 | PXD013746 | Pride
Inflammatory responses and immune regulation in bladder cancer treatment are critical to therapeutic efficacy, yet their specific mechanisms and protein-level changes remain unclear. Previous studies have shown that an immunosuppressive tumor microenvironment and excessive neutrophil infiltration le...
ORGANISM(S): Mus Musculus 
2025-11-05 | PXD070387 |
Proteomics data of targets identification of Danhong injection(10plex TMT)
ORGANISM(S): Homo Sapiens 
2024-06-04 | PXD052842 |
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