MacLean Andrew J AJ

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Unknown (7)
Metabolomics (2)
Proteomics (1)

Organisms

Homo sapiens (1)
Human immunodeficiency virus 1 (1)

Repository

MetaboLights (2)
pride (1)

Technology Type

Mass spectrometry (2)
Mass Spectrometry (1)
Shotgun proteomics (1)

Instrument Platform

Flow injection analysis MS - negative (1)
Flow injection analysis MS - positive (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - positive - hilic (1)
Liquid Chromatography MS – negative - hilic (1)
Liquid Chromatography MS – positive - reverse phase (1)

Publication Date

2023 (2)
2020 (1)

CHEBI ID

CHEBI:10072 (1)
CHEBI:1148 (1)
CHEBI:11814 (1)
CHEBI:12936 (1)
CHEBI:12962 (1)
CHEBI:133083 (1)
CHEBI:1387 (1)
CHEBI:14314 (1)
CHEBI:144330 (1)
CHEBI:15318 (1)
CHEBI:15344 (1)
CHEBI:15346 (1)
CHEBI:15351 (1)
CHEBI:15354 (1)
CHEBI:15355 (1)
CHEBI:15380 (1)
CHEBI:15414 (1)
CHEBI:15422 (1)
CHEBI:15468 (1)
CHEBI:1547 (1)
CHEBI:15473 (1)
CHEBI:15487 (1)
CHEBI:15517 (1)
CHEBI:15531 (1)
CHEBI:15533 (1)
CHEBI:15539 (1)
CHEBI:15551 (1)
CHEBI:15552 (1)
CHEBI:15555 (1)
CHEBI:15584 (1)

Metabolite Name

(4R)-4-Hydroxy-L-glutamic acid (1)
(R)-3-Hydroxybutyric acid (1)
(S)-3-Hydroxybutyric acid (1)
1,3-Diaminopropane (1)
1-Methyl-L-histidine (1)
1-Methylhistamine (1)
1-Methylnicotinamide (1)
2,3-Dihydroxypropanoic acid (1)
2,3-Dihydroxypropyl hexopyranoside (1)
2,3-Diphospho-D-glyceric acid (1)
2,3-Pyridinedicarboxylic acid (1)
2,5-Dihydroxybenzaldehyde (1)
2,5-Dihydroxybenzoic acid (1)
2-(Hydroxymethyl)butanoic acid (1)
2-Amino-3-methoxybenzoic acid (1)
2-Aminoadipic acid (1)
2-Deoxy-5-cytidylic acid (1)
2-Deoxy-D-ribonic acid (1)
2-Deoxy-D-ribose (1)
2-Deoxyadenosine (1)
2-Deoxyadenosine 5-triphosphate (1)
2-Deoxycytidine (1)
2-Deoxycytidine 5-diphosphate (1)
2-Deoxyguanosine (1)
2-Deoxyguanosine 5-diphosphate (1)
2-Deoxyguanosine 5-triphosphate (1)
2-Deoxyinosine (1)
2-Deoxyribose-5-phosphate (1)
2-Deoxyuridine (1)
2-Deoxyuridine 5-monophosphate (1)

Release Date

2023 (2)
2021 (2)
2025 (1)
2022 (1)
2020 (1)

Lab affiliation

Assistant Professor, Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA (1)

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Overcoming steric restrictions of VRC01 HIV-1 neutralizing antibodies through immunization

Broadly HIV-1 neutralizing VRC01-class antibodies target the CD4-binding site of Env. They are derived from VH1-2*02 antibody heavy chains paired with rare light chains expressing five amino acid long CDRL3s. They have been isolated from infected subjects but have not yet been elicited by immunizati...

ORGANISM(S): Human immunodeficiency virus 1 Homo sapiens

2020-05-26 | PXD015168 | Pride

Simultaneously discovering the fate and biochemical effects of pharmaceuticals through untargeted metabolomics

Untargeted metabolomics is an established approach in toxicology for characterising endogenous metabolic responses to xenobiotic exposure. Detecting the xenobiotic and its biotransformation products as part of the metabolomics analysis provides an opportunity to simultaneously gain deep insights int...

2023-07-03 | MTBLS2746 | MetaboLights

Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights

Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure: The REST Randomized Clinical Trial.

Not available

S-EPMC8408762 | biostudies-literature

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.

Not available

S-EPMC10208981 | biostudies-literature

Whole-genome sequencing reveals host factors underlying critical COVID-19.

Not available

S-EPMC9259496 | biostudies-literature

Mapping the human genetic architecture of COVID-19.

Not available