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ProteomicsModeling CRL4A ligase complex to predict target protein ubiquitination induced by CRBN-recruiting PROTACs
PROteolysis TArgeting Chimeras (PROTACs) are bifunctional small molecules that can simultaneously recruit target protein and E3 ligase to form a ternary complex (target protein / PROTAC / E3 ligase), leading to target protein ubiquitination and degradation via the Ubiquitin-Proteasome System (UPS). ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-19 | PXD030213 | Pride
Tmt Protac Ubiqutination 
ProteomicsDistinct transcriptomic and proteomic profile specifies heart failure patients with potential of myocardial recovery upon circulatory support and mechanical unloading
Phosphoproteomic Analysis of LVAD assisted human heart samples.
ORGANISM(S): Homo sapiens (Human) 
2023-02-27 | PXD016761 | Pride
Heart Phosphoproteomics Human 
ProteomicsTop-down proteomic analysis with FAIMS of Alzheimer's disease derived brain tissue
Proteomic datasets collected from a single human midfrontal cortex tissue sample. Tissue was homogenized in 8 M Urea, 10 mM ABC, and 10 mM TCEP before subsequent cleanup with 100K and 3K MWCO filters. NanoLC was performed for RP separation. Three technical replicates were collected without FAIMS. Se...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-14 | MSV000086696 | MassIVE
ProteomicsmLST8-CCT DSS crosslinking mass spectrometry
DSS crosslinking of mLST8-CCT purified from HEK293T cells using a tandem affinity approach. First cell extract was run over HisTrap column then a streptactin column.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-05-22 | MSV000083839 | MassIVE
ProteomicsBBSome Core Complex
Chemical crosslinking coupled with mass spectrometry data for the BBSome Core Complex
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-08-22 | MSV000081472 | MassIVE
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