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TranscriptomicsFine scale genetic mapping of a Hybrid Male Sterility factor between Drosophila simulans and D. mauritiana
see publication, arrays from 4 sterile genotypes containing homozygous segments with a Hybrid Male Sterility factor and 1 fertile strain in which the region is a Drosophila simulans and D. mauritiana heterozygous Dye swaps, loop design.
ORGANISM(S): Drosophila melanogaster 
2011-03-07 | E-GEOD-25339 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomic profiling of seminal plasma in nonobstructive azoospermia men: A noninvasive detection of spermatogenesis
Male factor infertility is involved in almost half of all infertile couples. Lack of the ejaculated sperm owing to testicular malfunction has been reported in 6-10% of infertile men, a condition named nonobstructive azoospermia (NOA). In this study, we investigated untargeted metabolomic profiling o...
2018-04-19 | MTBLS420 | MetaboLights
TranscriptomicsTesticular gene expression profiles in infertile patients with AZFc deletions of the Y chromosome
In the present study we carried out testicular gene expression profiling of patients with AZFc microdeletion, idiopathic infertility and normal spermatogenesis, in order to identify up- and downregulated genes in the different conditions, and to verify the presence of specific molecular pathways le...
ORGANISM(S): Homo sapiens 
2010-10-04 | E-GEOD-14310 | biostudies-arrayexpress
ProteomicsProteomic analysis of human sperm protamines from men with and without infertility
The objective of this study was to provide a comprehensive assessment of protamine isoforms and modifications in human sperm with the aim of identifying how protamine modifications/isoforms are altered in men with reduced sperm motility and low sperm count. Sperm samples from 18 men with prior repor...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD046041 | Pride
Male-factor infertility Sperm Protamines 
UnknownSperm centriole assessment identifies male factor infertility in couples with unexplained infertility - a pilot study.
Not available
S-EPMC9692136 | biostudies-literature
UnknownDuration of infertility and assisted reproductive outcomes in non-male factor infertility: can use of ICSI turn the tide?
Not available
S-EPMC9706853 | biostudies-literature
TranscriptomicsTranscription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male mice
Maintenance and maturation of primordial germ cells is controlled by complex genetic and epigenetic cascades, and disturbances in this network lead to either infertility or malignant aberration. Transcription factor Tcfap2c / TFAP2C has been described to be essential for primordial germ cell mainten...
ORGANISM(S): Mus musculus 
2014-01-30 | E-GEOD-45941 | biostudies-arrayexpress
UnknownRisk of diabetes according to male factor infertility: a register-based cohort study.
Not available
S-EPMC5850522 | biostudies-literature
TranscriptomicsEnvironmentally Induced Epigenetic Transgenerational Inheritance of Altered Sertoli Cell Transcriptome and Epigenome: Molecular Etiology of Male Infertility
Environmental toxicants have been shown to induce the epigenetic transgenerational inheritance of adult onset disease, including testis disease and male infertility. The exposure of a gestating female during the period of gonadal sex determination has been shown to promote sperm epimutations, diffe...
ORGANISM(S): Rattus norvegicus 
2012-09-27 | E-GEOD-41173 | biostudies-arrayexpress
UnknownUnderstanding general public and healthcare provider knowledge gaps in male factor infertility.
Not available
S-EPMC11833537 | biostudies-literature
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