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A novel class of genes has recently been identified as anticancer genes, which upon ectopic overexpression selectively destroy the transformed tumour cells, while leaving the untransformed normal cells unharmed. Examples include TRAIL, PAR4 and Orctl3. We have isolated 16 novel anticancer genes of h...
ORGANISM(S): Chlorocebus aethiops 
Integrity of the blood-brain barrier (BBB) is critical for brain homeostasis, and its malfunction contributes to neurovascular and neurodegenerative disorders. So far, mechanistic studies on BBB function have been mostly conducted in rodent and non-physiological in vitro models, which recapitulate s...
ORGANISM(S): Homo sapiens (Human) 
2025-09-08 | PXD066414 | Pride
To identify the molecular and cellular pathways mediating the effects of Foxf2 in brain endothelial cells (BECs), we performed proteomic analysis of mouse BECs. For this, we applied our previously published BEC enrichment protocol using magnetic-activated cell sorting (MACS) combined with liquid chr...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-02 | PXD051838 | Pride
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