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TranscriptomicsssDNA in S phase compared to G1 phase at different timepoints
To identify origins of replication in Lachancea waltii by mapping regions of ssDNA that are enriched in S phase. L. waltii cells are grown in the presence of hydroxyurea, which slows replication forks and causes the accumulation of ssDNA at the replication fork.
ORGANISM(S): Lachancea waltii 
2012-05-09 | E-GEOD-35253 | biostudies-arrayexpress
UnknownEpimural Indicator Phylotypes of Transiently-Induced Subacute Ruminal Acidosis in Dairy Cattle.
Not available
S-EPMC4777738 | biostudies-literature
ProteomicsNuclear-capture of endosomes drives depletion of nuclear G-actin to promote SRF/MRTF gene expression and cancer cell invasiveness.
Signals are relayed from receptor tyrosine kinases (RTKs) at the cell surface to effector systems in the cytoplasm and nucleus, and coordination of this process is important for the execution of migratory phenotypes, such as cell scattering and invasion. The endosomal system influences how RTK sign...
ORGANISM(S): Homo sapiens (Human) 
2021-09-28 | PXD027217 | Pride
Invasiveness Serum-response factor (srf) Cell:cell repulsion Epha2 Heptocyte growth factor (hgf) Rab17 Actin polymerisation Myocardin-related transcription factor (mrtf) Nuclear g-actin Nuclear import Pancreatic adenocarcinoma (pdac) 
UnknownEffectiveness of a home-based therapeutic exercise program on lower back pain and functionality in Sickle Cell Disease (SCD) patients.
Not available
S-EPMC8446254 | biostudies-literature
ProteomicsComparative analysis of WT CBL and CBL 70Z interactomes.
Cbl (Casitas B-lineage lymphoma) is a prominent post-translational regulator of protein tyrosine kinases (PTKs) that targets activated receptors for ubiquitination-mediated degradation. However, mutations within its E3 ubiquitin ligase activity rendering RING domain are often not sufficient to induc...
ORGANISM(S): Homo sapiens (Human) 
2021-02-26 | PXD011369 | Pride
On-beads digestion. Rtks Ubiquitination Cbl Label-free quantitation Endosomal trafficking 
TranscriptomicsDensity Transfer Data for Lachancea waltii DNA Replication Profile
Array data detailing the progression of DNA replication in the yeast Lachancea waltii. L. waltii cells were pregrown in heavy isotope medium and synchronized at early S phase. They were then released into normal medium, wherein DNA replication proceeds. Replicated DNA molecules are thus of heavy-lig...
ORGANISM(S): Lachancea waltii 
2012-05-09 | E-GEOD-35155 | biostudies-arrayexpress
ProteomicsSILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers
Abstract: Proteomics has been successfully used for cell culture on dishes, but more complex cellular systems have proven to be challenging and so far poorly approached with proteomics. Because of the complexity of the angiogenic program, we still do not have a complete understanding of the molecula...
ORGANISM(S): Homo sapiens (Human) 
2013-09-04 | PXD000359 | Pride
Angiogenesis Silac Huvecs Lc-ms/ms 
ProteomicsInteracting partners of Rac1 (P29S/Q61L) compared to constitutively active Rac1 (Q61L)
Interactors of double mutant Rac1 (P29S/Q61L) compared to constitutively active Rac1 (Q61L).
ORGANISM(S): Chlorocebus sabaeus 
2019-11-12 | PXD013941 | Pride
Cos7 cells Rac1 Gfp trap pulldown 
ProteomicsIn vivo SILAC-based proteomics reveals phosphoproteome changes during mouse skin carcinogenesis
Cancer progresses through distinct stages and mouse models recapitulating traits of this progression are frequently used to explore genetic, morphological and pharmacological aspects of tumor development. To complement genomic investigations of this process, here we quantify phosphoproteomic changes...
ORGANISM(S): Mus musculus (Mouse) 
2013-03-13 | PXD000821 | Pride
Mouse Silac Phosphoproteomics Skin carcinogenesis 
UnknownMetatranscriptome Sequencing Reveals Insights into the Gene Expression and Functional Potential of Rumen Wall Bacteria.
Not available
S-EPMC5787071 | biostudies-literature
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