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ProteomicsMetabolisme of artemisinin-resistant falciparum malaria parasites: are apicoplast and mitochondrion pathways key targets?
In the context of artemisinin resistance, the objective of the project was to evaluate the role of apicoplast and mitochondrion pathways during the parasite quiescent state induced by dihydroartemisinin (DHA) treatment. We analysed the proteome of artemisinin-resistant parasites in two conditions: a...
ORGANISM(S): Plasmodium falciparum 
2025-05-06 | PXD048354 | Pride
Artemisinin resistance  metabolism  apicoplast  mitochondrion  quiescence 
ProteomicsHuman Cytomegalovirus modifies placental small extracellular vesicle secretion and composition to enhance infection of fetal recipient cells
Human cytomegalovirus (hCMV) primo-infection, reinfection and/or reactivation is a major issue during pregnancy and affects 1% of live births in western countries, making hCMV the most frequently transmitted virus in utero. Despite the extensive research conducted so far, the pathophysiology of this...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Homo sapiens (Human) 
2022-10-13 | PXD029146 | Pride
Neural stem cells Hcmv Congenital infection Extracellular vesicles Placenta Cytotrophoblast 
ProteomicsProteomics of murine melanoma tumor cells upon sphingosine kinase-1 inhibition
In order to assess the impact of sphingosine kinase-1 (SK1) expression on melanoma growth, stable SK1 knockdown cells were generated by shRNA, using Yumm 1.7 cells derived from spontaneous murine melanoma driven by Braf activation as well as Pten and Cdkn2a inactivation. Two cell lines silenced for ...
ORGANISM(S): Mus musculus (Mouse) 
2019-12-17 | PXD016535 | Pride
Sphingosine kinase-1 Shotgun proteomics Murine cell line Melanoma 
ProteomicsQuest for missing proteins in the human spermatozoa: an update
Here, we report work as part of C-HPP initiatives on chromosomes 14 (France) and 2 (Switzerland) aiming to identify missing proteins in ejaculated human spermatozoa using multiple MS-based and antibodies-based validation approaches
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080826 | MassIVE
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