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ProteomicsHuman RNA ligase 1 as a novel regulator of ribosome function and translation under oxidative stress
Human RNA ligase 1 (Rlig1) is a recently identified human 5’-3’ RNA ligase essential for maintaining 28S rRNA integrity and promoting cell survival under oxidative stress. Although the enzymatic activity of Rlig1 implies a role in RNA maintenance or repair, its broader molecular context remains insu...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD067856 | Pride
Q-exactive hf Angel2 In-solution digest Ampylation Human Dis3 Rlig1 Clp1 Rna ligase Hek293 Dia Ribosome Enrichment Oxidative stress Exosome Ap-ms Rna repair 
ProteomicsHuman RNA ligase 1 as a novel regulator of ribosome function and translation under oxidative stress
Human RNA ligase 1 (Rlig1) is a recently identified human 5’-3’ RNA ligase essential for maintaining 28S rRNA integrity and promoting cell survival under oxidative stress. Although the enzymatic activity of Rlig1 implies a role in RNA maintenance or repair, its broader molecular context remains insu...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD067615 | Pride
Ribosome Xl-ms Rna repair Rlig1 
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