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MetabolomicsThe Leiden Longevity Study: Identification of biomarkers of the rate of ageing
The aim of the study is to identify genetic mechanisms of longevity and to characterize their interaction with the environment. Using the results the future health of people without familial longevity can be improved in old age. Long-lived siblings of European descent were recruited together with th...
2019-07-11 | MTBLS974 | MetaboLights
ProteomicsPhosphorylation site mapping on purified mGluR8/arrestin complexes
phosphorylation sites of purified mGluR8 with arrestin are mapped by mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2026-08-22 | PXD055267 | Pride
Neuronal receptor Gpcr Phosphorylation Metabotropic glutamate receptor 8 
UnknownDNA Damage Response/TP53 Pathway Is Activated and Contributes to the Pathogenesis of Dilated Cardiomyopathy Associated With LMNA (Lamin A/C) Mutations.
Not available
S-EPMC6460911 | biostudies-literature
UnknownStrategic approaches to unraveling genetic causes of cardiovascular diseases.
Not available
S-EPMC3115927 | biostudies-literature
UnknownA rare loss-of-function SCN5A variant is associated with lidocaine-induced ventricular fibrillation.
Not available
S-EPMC4105333 | biostudies-literature
UnknownAir Pollutants and Breast Cancer Risk: A Parallel Analysis of Five Large US Prospective Cohorts.
Not available
S-EPMC12614024 | biostudies-literature
UnknownHuman molecular genetic and functional studies identify TRIM63, encoding Muscle RING Finger Protein 1, as a novel gene for human hypertrophic cardiomyopathy.
Not available
S-EPMC3482312 | biostudies-literature
UnknownGenetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy.
Not available
S-EPMC2767296 | biostudies-literature
TranscriptomicsGenome-associated RNA Polymerase II includes the dissociable Rpb4/7 subcomplex
Yeast RNA polymerase (Pol) II consists of a ten-subunit core enzyme and the Rpb4/7 subcomplex, which is dispensable for catalytic activity and dissociates in vitro. To investigate whether Rpb4/7 is an integral part of DNA-associated Pol II in vivo, we used chromatin immuno-precipitation coupled to h...
ORGANISM(S): Saccharomyces cerevisiae 
2008-07-29 | E-GEOD-12060 | biostudies-arrayexpress
TranscriptomicsSlx5_Slx8_Genome_Stability
The Saccharomyces cerevisiae Slx5/8 complex is the founding member of a recently defined class of ubiquitin ligases (STUbLs) that target sumoylated substrates. Slx5/8 has been implicated in genome stability and transcription, but the precise contribution to these processes is not clear. To character...
ORGANISM(S): Saccharomyces cerevisiae 
2013-08-06 | E-GEOD-33929 | biostudies-arrayexpress
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