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GenomicsInterplay Between Active Chromatin Marks and RNA-directed DNA Methylation in Arabidopsis thaliana
DNA methylation is an epigenetic mark that is associated with transcriptional repression of transposable elements and protein coding genes. Conversely, transcriptionally active regulatory regions are strongly correlated with histone 3 lysine 4 di- and trimethylation (H3K4m2/3). We previously showed ...
ORGANISM(S): Arabidopsis thaliana 
2013-11-01 | E-GEOD-49090 | biostudies-arrayexpress
TranscriptomicsGain of chromatin loops marks the exit from naïve pluripotency – in-situ Hi-C data
In-situ Hi-C data for mouse embryonic stem cells (ES cells, grown in the presence of FBS and LIF) and for NS cells.
ORGANISM(S): Mus musculus 
2018-11-08 | E-MTAB-6591 | biostudies-arrayexpress
TranscriptomicsStrome UP07448_H3K27ME124439_N2_EEMB
modENCODE_submission_3179 This submission comes from a modENCODE project of Jason Lieb. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: The focus of our analysis will be elements that specify nucleosome positioning and occupancy, control domains of gene expressi...
ORGANISM(S): Caenorhabditis elegans 
2011-01-17 | E-GEOD-26178 | biostudies-arrayexpress
ProteomicsTwo H3K23 histone methyltransferases, SET-32 and SET-21, function synergistically to promote nuclear RNAi-mediated transgenerational epigenetic inheritance in Caenorhabditis elegans
Nuclear RNAi in C. elegans induces a set of transgenerationally heritable marks of H3K9me3, H3K23me3, and H3K27me3 at the target genes. The function of H3K23me3 in the nuclear RNAi pathway is largely unknown due to the limited knowledge of H3K23 histone methyltransferase (HMT). In this study we iden...
ORGANISM(S): Caenorhabditis elegans 
2024-12-06 | PXD052034 | Pride
C elegans Rnai Set-21 H3k23me3 Methyltransferase 
ProteomicsARID1A regulates chromatin organization and establishment of epigenetic marks for DSB repair and transcription silencing
AT-rich interactive domain-containing protein 1A (ARID1A), a SWI/SNF chromatin remodeling complex subunit, is frequently mutated across various cancer entities. ARID1A contributes to DNA damage response pathways, and we previously reported that ARID1A loss is associated with mutational signatures li...
ORGANISM(S): Homo sapiens (Human) 
2025-04-08 | PXD046159 | Pride
Epigenetics Hr Arid1a Dsb Chromatin 
ProteomicsARID1A regulates chromatin organization and establishment of epigenetic marks for DSB repair and transcription silencing
AT-rich interactive domain-containing protein 1A (ARID1A), a SWI/SNF chromatin remodeling complex subunit, is frequently mutated across various cancer entities. ARID1A contributes to DNA damage response pathways, and we previously reported that ARID1A loss is associated with mutational signatures li...
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD047225 | Pride
Dsb repair Epigenetic regulation Arid1a Chromatin 
GenomicsGenetic Adaptation of C. elegans to Environment Changes II: Multigenerational Analysis of Genome-wide Chromatin Remodeling
Chemical modifications to the tails of histone proteins act as gene regulators that play a pivotal role in adaptive responses to environmental stress. Determining the short and long term kinetics of histone marks is essential for understanding their functions in adaptation. We used Caenorhabditis el...
ORGANISM(S): Caenorhabditis elegans 
2021-07-09 | GSE103775 | GEO
TranscriptomicsChIP-seq of Atlantic salmon (Salmo salar) gill exposed to varying winter length
The experiment is designed to assess the impact of winter length on epigenetic status of key genes related to smoltification. Transferring fish from constant light (LL) to short photoperiod (SP) for different durations and then returning to constant light (LL) for 8 weeks to stimulate smoltification...
ORGANISM(S): Salmo salar 
2023-10-27 | E-MTAB-11091 | biostudies-arrayexpress
GenomicsCircadian cycling of genome-wide histone methylation
Daily (circadian) clocks are essential for regulating and coordinating physiology in mammals. Modulation of local chromatin structure has been shown for only a small number of genes, principally thought to be directly modulated by Clock-mediated histone acetylation. Here we show that genome-wide cha...
ORGANISM(S): Mus musculus 
2013-01-08 | E-GEOD-23550 | biostudies-arrayexpress
UnknownComputational and experimental determination of electrochemical standard rate constant from cyclic voltammetry: insights into <i>α</i> + <i>β</i> = 1 systems.
Not available
S-EPMC12706729 | biostudies-literature
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