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MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine UPLC-MS assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non relevant doses or in combination with other r...
2019-05-28 | MTBLS596 | MetaboLights
TranscriptomicsTranscription profiling of expressed human chromosome 21 genes in transchromosomic mouse embryos carrying a freely segregating copy of Hsa21
Detection of expressed human chromosome 21 genes in transchromosomic mouse embryos carrying a freely segregating copy of Hsa21.
ORGANISM(S): Mus musculus 
2005-11-19 | E-MEXP-409 | biostudies-arrayexpress
TranscriptomicsThe dikaryon formation (mating) transcriptome of the basidomycete fungus Coprinopsis cinerea (Coprinus cinereus)
Mating compatibility in C. cinerea is controlled by two loci, A and B. Following fusion of undifferentiated hyphal cells, a complex program is initiated which results in the maintenance of one nucleus from each parent in every cell (the dikaryon). We identified downstream targets of the A locus (A...
ORGANISM(S): Coprinopsis cinerea 
2010-06-21 | E-GEOD-20628 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of indole-3-acetic acid at physiological concentrations (IAA) treatment of Arabidopsis seedlings
To demonstrate the analysis of differential expression using CATMA v1 arrays, Arabidopsis seedlings were treated with indole-3-acetic acid at physiological concentrations. The seedlings were germinated in liquid medium, and treated with indole-3-acetic acid for 30, 120 or 240 minutes. Changes in exp...
ORGANISM(S): Arabidopsis thaliana 
2004-05-31 | E-MEXP-65 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
TranscriptomicsTranscription profiling of Arabidopsis mutants (elo2, elo3, drl1-2 and ang4) vs the wild type Ler strain
Microarray transcript profiling and RNA interference are two new technologies crucial for large-scale gene function studies in multicellular eukaryotes. Both rely on sequence-specific hybridization between complementary nucleic acid strands, inciting us to create a collection of gene-specific sequen...
ORGANISM(S): Arabidopsis thaliana 
2004-05-07 | E-MEXP-30 | biostudies-arrayexpress
TranscriptomicsEffect of hepatocyte-restricted deletion of FGF21 on subcutaneous white adipose tissue gene expression in fasting mice
FGF21 is a liver-derived hormone. FGF21 expression and secretion from hepatocytes is potently induced in response to fasting. However, the significance of such fasting-induced hepatokine production is poorly understood. Here, we investigated the putative effect of hepatocyte-derived FGF21 on fasting...
ORGANISM(S): Mus musculus 
2026-10-20 | E-MTAB-15880 | biostudies-arrayexpress
TranscriptomicsEffect of hepatocyte-restricted deletion of fgf21 deletion on perigonadic white adipose tissue gene expression in response to fasting in mice
FGF21 is a liver-derived hormone. It is potently induced and secreted in response to fasting. However, the biological significance of this endocrine response remains poorly understood. Here, we investigated the effect of hepatocyte FGF21 on perigonadic white adipose tissue biology through the analys...
ORGANISM(S): Mus musculus 
2026-10-20 | E-MTAB-15878 | biostudies-arrayexpress
TranscriptomicsEffect of hepatocyte FGF21 on brown adipose tissue gene expression in mice
FGF21 is an hepatokine, a liver-derived hormone, that is highly induced and secreted in response to fasting. We investigated the role of hepatic FGF21 on gene expression profile in the brown adipose tissue. The effect of 20h fasting on brown adipose tissue gene expression was investigated in male wi...
ORGANISM(S): Mus musculus 
2026-10-17 | E-MTAB-15855 | biostudies-arrayexpress
TranscriptomicsEffect of hepatocyte-restricted deletion of fgf21 deletion on liver gene expression in response to fasting in mice
FGF21 is a liver-derived hormone potently induced in response to fasting. However, its role in the regulation of hepatic gene expression is unknown. The effect of 20h fasting on liver gene expression was investigated in wild-type mice and in mice lacking hepatocyte FGF21. Fgf21 hepatocyte-specific ...
ORGANISM(S): Mus musculus 
2026-10-16 | E-MTAB-15848 | biostudies-arrayexpress
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