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ProteomicsIn-depth proteome analysis of human ascites using high-pH peptide fractionation
For in-depth profiling, ascites from patients with benign disease or gastric cancer were subjected to high-resolution mass spectromtery analysis. By high-pH peptide fractionation, 3481 protein groups were identified in 72 LC-MS/MS runs.
ORGANISM(S): Homo sapiens (Human) 
2018-04-16 | PXD003351 | Pride
Ascites High-ph peptide fractionation Gastric cancer 
ProteomicsPine Golgi membranes from xylem enriched by FFE
Developing xylem from strong and mild compression wood of Pinus radiata were harvested and Golgi membranes enriched by density centrifugation. Enriched membranes were further purified by free-flow electrophoresis. A total of 3 fractions were collected (from each tissue) and analyzed by tandem mass ...
ORGANISM(S): Pinus radiata (Monterey pine) 
2014-04-14 | PXD000557 | Pride
Golgi Pine Ffe Xylem Compression wood 
ProteomicsA PTM-centric Proteome Informatic Pipeline for Monitoring Post-Translational Modifications by PEIMAN2
Post-translational modifications (PTMs) are under significant focus in molecular biomedicine due to their importance in signal transduction in most cellular and organismal processes. Identification of PTMs, determination of PTM location sites, discrimination between functional and inert PTMs, and qu...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD037681 | Pride
Ptm Proteomics Mass spectromtery 
ProteomicsHuman corneal epithelial cells internalize Aspergillus flavus spores by actin mediated endocytosis
Mycotic leratitis is the corneal inflammation predominantly caused by Fusarium and Aspergillus species. Corneal epithelium is the earliest cell type encounter the invading pathogen. The innate immune responses of human corneal epithelial cells against Aspergillus flavus is not known. Here we studied...
ORGANISM(S): Homo sapiens (Human) 
2021-04-07 | PXD019512 | Pride
Corneal epithelium Actin ring Asperillus flavus Phagosome 
ProteomicsTranscriptome, proteome, and metabolome of lens fiber cells from mice exposed to cigarette smoke
We adopted an omics (transcriptome, proteome, and metabolome) approach to characterize the lens fiber cells extracted from control (CT) and cigarette smoke (CS) exposed mouse (C57BL/6) eyes. The eight pregnant female mice (gestation days 19-20) were placed in a whole-body exposure smoking chamber an...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-15 | PXD017414 | Pride
Mouse Metabolome Mass spectromtery Proteome Transcriptome 
GenomicsShewanella oneidensis MR-1
Response in Shewanella oneidensis MR-1 and so2426 deletion mutant to Hexavalent Chromium over a 24 hour period
PRJNA113489 | ENA
ProteomicsSingle locus phosphoproteomics reveals phosphorylation of RPA-1 is required for generation of single-strand DNA following a break at a subtelomeric locus
Damage to the genetic material of the cell poses a universal threat to all forms of life. Central to the DNA damage response (DDR) is a phosphorylation signalling cascade that leads to the co-ordination of the cellular response to a DNA break. Identifying the proteins that are phosphorylated is cruc...
ORGANISM(S): Trypanosoma brucei 
2024-09-04 | PXD034455 | Pride
Trypanosoma brucei Phosphoproteomics Silac Dna damage 
ProteomicsPfcerli2, a duplicated gene in the malaria parasite Plasmodium falciparum essential for invasion of erythrocytes as revealed by phylogenetic and cell biological analysis.
Merozoite invasion of host red blood cells (RBCs) is essential for survival of the human malaria parasite Plasmodium falciparum. Proteins involved with RBC binding and invasion are secreted from dual-club shaped organelles at the apical tip of the merozoite called the rhoptries. Here we characterise...
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum 
2021-11-15 | PXD028937 | Pride
Plasmodium falciparum Malaria Human red blood cells 
ProteomicsFilling the gaps – a call for comprehensive analysis of extracellular matrix of the glial scar in region- and injury-specific contexts
CNS injury results in chronic scar formation that interferes with function and inhibits repair. Extracellular matrix (ECM) is prominent in the scar and potently regulates cell behavior. However, comprehensive information about the ECM proteome is largely lacking, and region- as well as injury-specif...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-27 | PXD017478 | Pride
Central nervous system Macrophages Gliosis Brain injury Scarring Extracellular matrix 
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