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ProteomicsMast cell intracellular traps (MIT) release neutrophil effector proteins during degranulation and nexocytosis
Degranulating mast cells (MCs) release inflammatory mediators (proteins, lipids, small molecules), including chemokines and chemoattractants, which recruit other immune cells in tissues. Neutrophils can initiate self-amplifying swarming responses via intercellular communication through the lipid leu...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-18 | PXD044140 | Pride
Proteomics of secreted proteins Neutrophiles Mast cells Secretome Entosis Mast cell intracellular traps 
UnknownMethadone Requires the Co-Activation of μ-Opioid and Toll-Like-4 Receptors to Produce Extracellular DNA Traps in Bone-Marrow-Derived Mast Cells.
Not available
S-EPMC10889600 | biostudies-literature
UnknownOpportunistic pathogen Candida albicans elicits a temporal response in primary human mast cells.
Not available
S-EPMC4507480 | biostudies-literature
UnknownHuman mast cells exhibit an individualized pattern of antimicrobial responses.
Not available
S-EPMC7212193 | biostudies-literature
TranscriptomicsTranscription profiling of diabetic vs non-diabetic human blood cells infected with Burkholderia pseudomallei
To gain insight into the role of glibenclamide treatment of diabetic patients in melioidosis (Burkholderia pseudomaleii infection)
ORGANISM(S): Homo sapiens 
2010-12-31 | E-TABM-852 | biostudies-arrayexpress
ProteomicsMudPIT analyses of the proteins purified by in vitro dCas9-targeted chromatin IP of telomere sequences in HeLa cells
We used a reverse chromatin immunoprecipitation (ChIP) method that takes advantage of the RNA-mediated DNA-targeting capability of Cas9 to efficiently and adaptably isolate specific genomic regions and their associated protein factors. By using purified recombinant catalytically-dead Cas9 (dCas9) co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-10-25 | MSV000081645 | MassIVE
ProteomicsMudPIT analyses of the proteins purified by in vitro dCas9-targeted chromatin IP of the fruit fly Histone Cluster
We used a reverse chromatin immunoprecipitation (ChIP) method that takes advantage of the RNA-mediated DNA-targeting capability of Cas9 to efficiently and adaptably isolate specific genomic regions and their associated protein factors. By using purified recombinant catalytically-dead Cas9 (dCas9) co...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2017-10-25 | MSV000081643 | MassIVE
TranscriptomicsDual RNA-seq of THP-1 macrophages infected with JE2 WT and ΔessC at 2 and 6 hours post infection
This experiment was conducted to uncover global transcription differences caused by Staphylococcal T7SS during early and mid-late macrophage infection.
ORGANISM(S): mixed sample 
2026-01-01 | E-MTAB-16250 | biostudies-arrayexpress
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