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All constructs were expressed in RKO cells (human rectal carcinoma cell line). A fusion construct of TurboID (mutated BirA* from E. Coli) and green fluorescent protein (GFP) or human TRIM52. Cells were stimulated with Epoxomicin (proteasome inhibitor) or left untreated. Biotinylated proteins were e...
ORGANISM(S): Homo sapiens (Human) 
2025-03-25 | PXD051272 | Pride
Members of the apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like (APOBEC) family play crucial roles as viral restriction factors, yet some APOBEC3 (A3) members drive harmful hypermutation in humans, contributing to cancer. These cancer-associated A3 members have reduced RNA-mediated r...
ORGANISM(S): Homo sapiens (Human) 
2025-12-22 | PXD051267 | Pride
Malaria is a disease targeting the most vulnerable people. It is caused by the parasite Plasmodium falciparum, and is transmitted to humans by Anopheles mosquitos during a blood meal, who are in turn infected by the parasite if they feed on an infected human. While current eradication efforts focus ...
ORGANISM(S): Plasmodium falciparum 58.1 Homo sapiens (Human) 
2026-04-09 | PXD067699 | Pride
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