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MetabolomicsMetabolomics analysis was used to resolve metabolites affecting the protein oil content of soybean.
Soybean (Glycine max (L.)) originated in China more than 5000 years ago, and the country is currently the third largest producer of soybeans in the world (Hymowitz et al., 2015). Based on a wild soybean Chromosome Segment Substitution Line (CSSL) population were constructed by crossing with the cult...
2024-11-13 | MTBLS9424 | MetaboLights
TranscriptomicsGlycine max Transcriptome or Gene expression
Virus Induced Gene Silencing (VIGS) was used to silence the expression of soybean Replication Protein 3 (GmRPA3). RNAseq was used to compare gene expression in GmRPA3 silenced and empty vector treated plants
ORGANISM(S): Glycine max 
2013-07-29 | E-MTAB-4354 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiling of Glycine max Cotyledons and Trifoliate Leaves to Determine Genes Associated with Senescence
We use RNA sequencing technology in a time course study to measure transcript abundance from three developmental stages in cotyledons and five stages in the trifoliate leaf of Glycine max to identify genes with distinct temporal patterns of expression during leaf or cotyledon development. We also ex...
ORGANISM(S): Glycine max 
2015-05-01 | E-GEOD-61857 | biostudies-arrayexpress
TranscriptomicsMax is a repressor of germ-cell-related gene expression in mouse embryonic stem cells
Embryonic stem cells (ESCs) and primordial germ cells (PGCs) express many pluripotency-associated genes, but ESCs do not normally undergo conversion into PGCs. Thus, we predicted that there is a mechanism that represses PGC-related gene expression in ESCs. Here we identify genes involved in this put...
ORGANISM(S): Mus musculus 
2013-05-01 | E-GEOD-45181 | biostudies-arrayexpress
TranscriptomicsEffect of ablation of Max gene expression on ES cells cultured under conventional or 2i/Nam condition.
c-Myc is one of key players that are crucially involved in maintaining the undifferentiated state and the self-renewal of ESCs. To understand the mechanism by which c-Myc helps preserve these prominent characteristics of ESCs, we generated null-ES cells for the Max gene, which encodes the best chara...
ORGANISM(S): Mus musculus 
2011-07-19 | E-GEOD-27881 | biostudies-arrayexpress
TranscriptomicsIdentification of MAX signature on MAX deficient SCLC cell lines
To development our gene expression approach, we have employed whole genome microarray expression profiling as a discovery platform to identify genes potentialy regulated by the transcription factor MAX.Human SCLC cell lines waere analyzed for mutations at the MAX locus. Those cell lines that were f...
ORGANISM(S): Homo sapiens 
2013-12-28 | E-GEOD-48559 | biostudies-arrayexpress
MetabolomicsMulti-omics profiling identifies MAPK signaling suppression associated with tetracycline-induced root toxicity in soybean
Tetracycline (TC), a widely used veterinary antibiotic, is a pervasive emerging contaminant threatening crop production. Here, we employed integrated physiological, metabolomic, and transcriptomic analyses to decipher the response of soybean (Glycine max L.) to TC. While seed germination was unaffec...
2026-09-07 | MTBLS15077 | MetaboLights
ProteomicsMAX-mutant small cell lung cancers exhibit impaired activities of MGA-dependent ncPRC1.6.
The MYC axis is commonly disrupted in cancer, mostly by activation of the MYC family of oncogenes, but also by genetic inactivation of MAX, the obligate partner of MYC, and of the MAX partner, MGA, both of which are members of the polycomb repressive complex, ncPRC1.6. While the oncogenic properties...
ORGANISM(S): Homo sapiens (Human) 
2021-09-22 | PXD017658 | Pride
Max-gene associated protein Proteomics Cell lung cancer Mga Immunoprecipitation Max 
TranscriptomicsGenome-wide transcriptome analyses of developing seeds from low and normal phytic acid soybean lines
Purpose: Comprehensive comparison of gene-expression profiles between 3mlpa (mutant with low phytic acid) and 3MWT (non-mutant with normal phyic acid) soybean lines (Glycine max) at five stages of seed development using RNA-Seq approaches. Methods: mRNA sequencing reads (101SE) were generated in tri...
ORGANISM(S): Glycine max 
2016-01-15 | E-GEOD-75575 | biostudies-arrayexpress
TranscriptomicsGlycine max Transcriptome or Gene expression
Soybean (Glycine max, cv Williams82) leaf petiole explants exposed to 25 ul/l ethylene for 0 to 72 h. Explants were prepared from 21 day-old greenhouse grown plants. Leaf abscission zones (LAZ) consisted of 2 mm of tissue collected below the leaf blade. The petioles (NAZ) consisted of approximately ...
ORGANISM(S): Glycine max 
2015-02-06 | E-MTAB-5066 | biostudies-arrayexpress
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