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UnknownPreclinical in vivo longitudinal assessment of KG207-M as a disease-modifying Alzheimer's disease therapeutic.
Not available
S-EPMC9014686 | biostudies-literature
TranscriptomicsParallel selection mapping using artificially selected mice reveals body weight control loci (gene expression)
Understanding how polygenic traits evolve and respond to selection is a major unsolved problem, because challenges exist for identifying genes underlying a complex trait and understanding how multi-locus selection operates in the genome. Here we used artificial selection experiments to study polygen...
ORGANISM(S): Mus musculus 
2012-06-29 | E-GEOD-36443 | biostudies-arrayexpress
UnknownUnderstanding Treatment Gaps for Mental Health, Alcohol, and Drug Use in South Dakota: A Qualitative Study of Rural Perspectives.
Not available
S-EPMC7324071 | biostudies-literature
ProteomicsChemical inhibition of the target of rapamycin kinase in Chlamydomonas reinhardtii leads to rapid cysteine oxidation and sustained physiological changes.
The target of rapamycin (TOR) kinase is a key metabolic regulator with a role in diverse processes, including nutritional sensing, protein translation, and autophagy. In the green alga Chlamydomonas reinhardtii, TOR maintains these responsibilities and is additionally linked to the regulation of inc...
ORGANISM(S): Chlamydomonas reinhardtii 
2019-10-04 | PXD014819 | Pride
Azd8055 Global proteomics Chlamydomonas reinhardtii Target of rapamycin Reversible cysteine oxidation 
ProteomicsProteome-wide analysis of cysteine reactivity in Arabidopsis associated with biotic stress response
We used a method for the enrichment of proteins with oxidative post-translational modifications that enabled the comprehensive identification and label-free quantification of reversibly oxidized thiols across the plant proteome. The redoxomes were characterized in wild-type and the top1top2 null mut...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-03-19 | PXD010104 | Pride
Arabidopsis thaliana Pseudomonas syringae Thimet oligopeptidase Redox proteomics Biotic stress 
ProteomicsThe ‘PepSAVI-MS’ pipeline for natural product bioactive peptide discovery
The recent increase in extensively drug resistant bacterial pathogens and the associated increase of morbidity and mortality demonstrate the immediate need for new antibiotic backbones with novel mechanisms of action. Here, we report the development of the PepSAVI-MS pipeline for bioactive peptide d...
ORGANISM(S): Viola odorata 
2017-01-02 | PXD004780 | Pride
Anticancer Mass spectrometry Antimicrobial peptides Antifungal Antimicrobial resistance Screening platform 
UnknownDoes Ownership Make a Difference in Primary Care Practice?
Not available
S-EPMC6566859 | biostudies-literature
UnknownThe superficial white matter in temporal lobe epilepsy: a key link between structural and functional network disruptions.
Not available
S-EPMC4995361 | biostudies-literature
UnknownTight Coupling between Morphological Features of the Central Sulcus and Somatomotor Body Representations: A Combined Anatomical and Functional MRI Study.
Not available
S-EPMC7132904 | biostudies-literature
ProteomicsReversible oxidative signaling in Chlamydomonas following nitrogen deprivation
As global temperatures climb to historic highs, the far-reaching effects of climate change have impacted agricultural nutrient availability. This has extended to low latitude oceans, where a deficit in both nitrogen and phosphorus stores has led to dramatic decreases in carbon sequestration in ocean...
ORGANISM(S): Chlamydomonas reinhardtii 
2020-06-28 | PXD019491 | Pride
Oxidation Ptm Lcms Signaling Chlamydomonas 
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