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TranscriptomicsHigh-resolution copy number analysis of medulloblastoma
We used high-resolution SNP genotyping to identify regions of genomic gain and loss in the genome of 212 medulloblastomas, a malignant pediatric brain tumor. Focal amplifications of fifteen known oncogenes and focal deletions of twenty known tumor suppressor genes (TSG) were revealed, most not prev...
ORGANISM(S): Homo sapiens 
2010-04-06 | E-GEOD-14437 | biostudies-arrayexpress
TranscriptomicsRNAseq of 6 medulloblastoma cell lines
Medulloblastoma is subdivided into different subgroups: WNt, SHH, Group 3 and Group 4. Since these subgroups are associated with different OS and metastasis rates it is crucial to understand them better. Six medulloblastoma cell lines, DAOY, ONS-76, D458, HD-MB03, CHLA-01-MED, CHLA-01R-MED, have bee...
ORGANISM(S): Homo sapiens 
2022-03-02 | E-MTAB-9823 | biostudies-arrayexpress
TranscriptomicsSubgroup specific somatic copy number aberrations in the medulloblastoma genome [gDNA]
Affymetrix SNP6 profiling of 1087 medulloblastoma samples and 10 medulloblastoma cell lines. Genomic DNA was extracted from primary medulloblastoma samples and medulloblastoma cell lines and hybridized to Affymetrix SNP6 arrays according to the manufacturer's instructions.
ORGANISM(S): Homo sapiens 
2012-07-26 | E-GEOD-37384 | biostudies-arrayexpress
ProteomicsProteogenomic Analysis of Medulloblastoma
In order to investigate medulloblastoma biology via its proteome, we undertook a super-SILAC quantitative proteomics survey using 41 clinical tissue samples spanning the 4 genomic subgroups and control cerebellum
ORGANISM(S): Homo sapiens (Human) 
2018-06-10 | PXD008750 | Pride
Medulloblastoma Brain tumor Silac Human Pediatrics 
ProteomicsD283 MED, a cell line derived from peritoneal metastatic medulloblastoma — a good choice for missing protein discovery
Our goal is the identification of more and more missing proteins from cancer cell lines. This project focuses on D283 med and U-118mg cell lines which contribute to 12 missing protein identification.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-06-21 | MSV000087678 | MassIVE
TranscriptomicsshRNA-mediated knock down of Bmi-1 and Mel-18 in medulloblastoma cells
Bmi-1 and Mel-18 are close structural homologues that belong to the polycomb group (PcG) of transcriptional regulators of homeotic gene expression in development. They are believed to stably maintain repression of gene expression by altering the state of chromatin at specific promoters. A number of...
ORGANISM(S): Homo sapiens 
2007-10-31 | E-GEOD-7578 | biostudies-arrayexpress
TranscriptomicsExpression profiling of human medulloblastoma cell line ONS76 upon siRNA-mediated knockdown of KDM5A/LSD1
KDM5A/LSD1 is an important epigenetic regulator in medulloblastoma, the most frequent brain tumor of childhood. Here, the response of ONS76 medulloblastoma cells upon siRNA-mediated knockdown of KDM5A is analysed. The expression profile of ONS76 cells upon KDM5A knockdown was compared to mock contro...
ORGANISM(S): Homo sapiens 
2013-08-01 | E-GEOD-43552 | biostudies-arrayexpress
TranscriptomicsExpression data of medulloblastoma cell lines with OCT4A overexpression
Medulloblastoma is a highly aggressive pediatric brain tumor, in which expression of the pluripotency factor OCT4 has been recently correlated with poor patient survival. However, the contribution of OCT4 transcript variants to tumor aggressiveness is still poorly understood. In this study, we found...
ORGANISM(S): Homo sapiens 
2016-02-17 | E-GEOD-77947 | biostudies-arrayexpress
ProteomicsMedulloblastoma LC-MS/MS using small extracellular vesicles from blood plasma, CSF, and MB cell lines
Liquid biopsy is increasingly recognized for tumor diagnosis and monitoring, and in medulloblastoma (MB) and other CNS tumors, it offers the potential to bypass invasive tissue collection. However, its application in clinical practice remains limited, in part because the optimal choice of biofluid i...
ORGANISM(S): Homo sapiens (Human) 
2025-09-22 | PXD067299 | Pride
Lc-ms/ms Medulloblastoma Medulloblastoma cell lines Blood plasma Small extracellular vesicles Csf 
GenomicsmiRNA expression profile in human medulloblastoma cell lines.
miRNA expression profile in human medulloblastoma cell lines.
PRJNA1004212 | ENA
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