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TranscriptomicsMeg3 regulated genes in pancreatic beta cells
Meg3 is a long non-coding RNA. It's target genes are unknown. The mouse pancreatic beta cell line MIN6-4N was used to assess the expression of genes upon stable Meg3 overexpression Stable cell lines were isolated that have integated pcDNA3.1 or pcDNA3.1-mMeg3.The cells were processed for RNA isolati...
ORGANISM(S): Mus musculus 
2015-05-21 | E-GEOD-57716 | biostudies-arrayexpress
GenomicsHerbaspirillum sp. meg3
Herbaspirillum sp. meg3 Genome sequencing
PRJNA397799 | ENA
ProteomicsThe RNA pulldown of MEG3 to identify RNA-binding proteins
By using biotinylated MEG3 and streptavidin-labeled magnetic beads, identify the RNA-binding proteins of MEG3.
ORGANISM(S): Homo sapiens (Human) 
2025-06-30 | PXD062094 | Pride
Meg3 Rna-pulldown Rna-binding proteins 
TranscriptomicsIncreased Expression of Angiogenic Genes in the Brains of Mouse Meg3-null Embryos
MEG3 (Maternally Expressed Gene 3) is a non-coding RNA that is highly expressed in the normal human brain and pituitary. Expression of MEG3 is lost in gonadotroph-derived clinically non-functioning pituitary adenomas. Meg3 knock-out mice were generated to identify targets and potential functions o...
ORGANISM(S): Mus musculus 
2010-12-17 | E-GEOD-18742 | biostudies-arrayexpress
GenomicsChIP-seq in MRC5 hIPSCs overexpressing MEG3 RNA.
This experiment was designed to detect differences in PRC2 occupancy in a human induced pluripotent cell line (MRC5) naturally deficient in MEG3 RNA after lentiviral overexpression of MEG3. MRC5 were transduced with lentiviruses for the overexpression of MEG3 lncRNA or GFP as a control. ChIP-seq was...
ORGANISM(S): Homo sapiens 
2013-12-25 | E-GEOD-48515 | biostudies-arrayexpress
TranscriptomicsSmall RNA-Seq of LSK Slam HSCs MxCre Control vs MxCre Meg3 flox (Meg3 KO)
Here, we present a Small RNA-Seq dataset of isolated mouse hematopoietic stem cells (HSC LSK slam; Lineage- Sca-1+ c-Kit+ CD150+CD48-) of Meg3 KO (induced MxCre Meg3mat flox/pat wt) and control (induced MxCre) cells
ORGANISM(S): Mus musculus 
2019-02-15 | E-MTAB-7519 | biostudies-arrayexpress
GenomicsUpregulation of the lncRNA MEG3 in Metastatic Hepatoblastoma
Upregulation of the lncRNA MEG3 in Metastatic Hepatoblastoma
PRJNA1403453 | ENA
GenomicsSmall RNA-Seq of LSK Slam HSCs MxCre Control vs MxCre Meg3 flox (Meg3 KO)
Small RNA-Seq of LSK Slam HSCs MxCre Control vs MxCre Meg3 flox (Meg3 KO)
PRJEB30342 | ENA
GenomicsChIP-seq in MEG3+ and MEG3- hIPSCs
In this experiment we sought to identify region with differential PRC2, JARID2, and H3K27me3 occupancy in human induced pluripotent stem cell lines with silenced or expressed MEG3 locus to indirectly determine the effect of this ncRNA on PRC2 function. 8 hIPSC lines, 5 MEG3+ and 3 MEG3-; ChIP-seq fo...
ORGANISM(S): Homo sapiens 
2013-12-25 | E-GEOD-48516 | biostudies-arrayexpress
GenomicsThe long non-coding RNA Meg3 mediates imprinted gene expression during stem cell differentiation
Meg3 lncRNA and imprinted gene expression
PRJEB57653 | ENA
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