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ProteomicsPrenatal low-dose MeHg exposure leads to proteomic and transcriptomic alterations consistent with neurodegenerative disease in the cerebellum of C57BL/6 mice
Methylmercury (MeHg) is a global pollutant that readily crosses the blood–brain barrier and placenta, posing significant risks to fetal neurodevelopment. While the cerebellum is a recognized target of MeHg toxicity in adults, the mechanisms underlying fetal exposure remain poorly defined. In this st...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-06 | PXD068503 | Pride
Proteomics Mehg Prenatal Disease latency Cerebellum Transcriptomics Neurodegenerative disease 
TranscriptomicsGene expression changes in the female zebrafish (Danio rerio) brain in response to acute exposure to methylmercury
Methylmercury (MeHg) is a potent neurotoxin and endocrine disruptor that accumulates in aquatic systems. Previous studies have shown suppression of hormone levels in both male and female fish, suggesting effects on gonadotropin regulation in the brain. We investigated the gene expression profile in ...
ORGANISM(S): Danio rerio 
2010-09-30 | E-GEOD-22662 | biostudies-arrayexpress
TranscriptomicsEffects of methylmercury on genome-wide gene expression in the liver of Atlantic cod (Gadus morhua)
Methylmercury (MeHg) is a highly toxic environmental pollutant. To understand the mechanisms of toxicity of the compound and possibly to discover new biomarkers for environmental monitoring, we have conducted toxicogenomics studies. We designed 126k-cod-oligonucleotide arrays and performed genome-wi...
ORGANISM(S): Gadus morhua 
2013-01-22 | E-GEOD-38746 | biostudies-arrayexpress
TranscriptomicsMeHg exposure zebrafish embryos vs control
Gene respons in the central nervous system of zebrafish embryos exposed to the neurotoxicant methyl mercury Two-condition experiment, control vs MeHg exposure embryos (60 µg/l), Biological replicates: 4, dye swaps
ORGANISM(S): Danio rerio 
2012-05-14 | E-GEOD-37970 | biostudies-arrayexpress
TranscriptomicsZebrafish transgenerational methylation profiling in response to TCDD, 5-AZA and MeHg
Adult F0 female zebrafish were fed with control diet or diets containing 5-AZA, MeHg or TCDD. After breeding with unexposed males to produce the F1 generation, livers were sampled from the F0 females. F1 generation embryos were unexposed to test chemicals, were sampled, then bred to produce F2 fish,...
ORGANISM(S): Danio rerio 
2014-03-01 | E-MTAB-2057 | biostudies-arrayexpress
TranscriptomicsToxic effects of dietary methylmercury (MeHg) on juvenile rainbow trout
Juvenile rainbow trout were fed Biodiet starter (4% body weight per day) with MeHg added at 0, 0.5, 5 and 50 ppm for six weeks. Atomic absorption spectrometry was applied to measure the level of MeHg in the whole fish body. Trout at six weeks were sampled from each group for gene expression analysis...
ORGANISM(S): Oncorhynchus mykiss 
2013-06-01 | E-GEOD-32429 | biostudies-arrayexpress
GenomicsPseudomonas fluorescens strain:XD-MeHg-B2
Pseudomonas fluorescens XD-MeHg-B2 genome sequencing
PRJNA546958 | ENA
TranscriptomicsToxic effects of dietary methylmercury (MeHg) on young adult zebrafish
Three-month old zebrafish were fed Biodiet starter (4% body weight per day) with MeHg added at 0, 0.5, 5 and 50 ppm for six weeks. Atomic absorption spectrometry was applied to measure the level of MeHg in the whole fish body. Zebrafish at six weeks were sampled from each group for gene expression a...
ORGANISM(S): Danio rerio 
2013-06-01 | E-GEOD-32430 | biostudies-arrayexpress
UnknownDiverse Methylmercury (MeHg) Producers and Degraders Inhabit Acid Mine Drainage Sediments, but Few Taxa Correlate with MeHg Accumulation.
Not available
S-EPMC9948709 | biostudies-literature
Genomicsmethylmercury (MeHg) producers and degraders in acid mine drainage sediments
methylmercury (MeHg) producers and degraders in acid mine drainage sediments Genome sequencing and assembly
PRJNA830440 | ENA
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