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TranscriptomicsTranscription profiling of wheat meiosis and microsporogenesis in hexaploid bread wheat
Our understanding of the mechanisms that govern the cellular process of meiosis is limited in higher plants with polyploid genomes. Bread wheat is an allohexaploid that behaves as a diploid during meiosis. Chromosome pairing is restricted to homologous chromosomes despite the presence of homoeologue...
ORGANISM(S): Triticum aestivum 
2008-06-14 | E-GEOD-6027 | biostudies-arrayexpress
ModelsRay2013 - S.cerevisiae meiosis-specific metabolic network
Ray2013 - S.cerevisiae meiosis-specific metabolic network Meiosis is a strongly concerved cell division program that generates haploid gametes from a diploid parental cell. Successful meiosis is the fundamental basis of sexual reproduction. Multiple lines of evidence suggest a tig...
2005-01-01 | MODEL1303140001 | BioModels
TranscriptomicsMonopolar attachment of sister kinetochores at meiosis I requires casein kinase 1.
The segregation of maternal centromeres away from the paternal ones during the first division of meiosis depends on the attachment of sister kinetochores to microtubules emanating from the same spindle pole. In budding yeast monopolar attachment requires the recruitment to kinetochores of a protein ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-10 | E-GEOD-4792 | biostudies-arrayexpress
TranscriptomicsTranscriptome Profile of CYC2 K.O. and WT during meiosis in Tetrahymena thermophila
Meiotic recombination is carried out through a specialized pathway for the formation and repair of DNA double-strand breaks (DSBs) made by the Spo11 protein. The present study shed light on the functional role of Cyclin, CYC2, in Tetrahymena thermophila which has transcriptionally high expression le...
ORGANISM(S): Tetrahymena thermophila 
2016-04-06 | E-GEOD-79286 | biostudies-arrayexpress
OtherThe nuclear exosome is active and important during budding yeast meiosis.
Data from ProteomeXchange, PXD ID: PXD001239. File: Meiosis_IP_rep.mzml. Published as part of PLoS One. 2014 Sep 11;9(9):e107648 . From the Abstract: {{i}} ... We have analysed the activity of the nuclear exosome during meiosis by deletion of TRF4, which encodes a key component of the exosome targe...
ORGANISM(S): Yeast 
GPM32310019869 | GPMDB
Resource Reanalysis 
TranscriptomicsScreening of genes involved in chromosome segregation in meiosis I
Prophase I of meiosis involves dynamic chromosome segregation processes including synapsis, meiotic recombination, and cohesion. Genetic defects in genes participating in these processes consistently cause reproduction failure in mice. To identify candidate genes responsible for infertility or recur...
ORGANISM(S): Mus musculus 
2012-06-03 | E-GEOD-35734 | biostudies-arrayexpress
TranscriptomicsAGO4 Regulates Entry into Meiosis and Influences Silencing of Sex Chromosomes in the Male Mouse Germline
The four mammalian Argonaute family members are thought to share redundant functions in the microRNA pathway, yet only AGO2 possesses the catalytic "slicer" function required for RNA interference. Whether AGO1, AGO3, or AGO4 possess specialized functions remains unclear. Here, we Series_su...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-39652 | biostudies-arrayexpress
TranscriptomicsScreening of genes involved in chromosome segregation in meiosis I
Prophase I of male meiosis involves dynamic chromosome segregation processes during early spermatogenesis, including synapsis, meiotic recombination, and cohesion. Genetic defects in genes participating in these processes consistently cause reproduction failure in mice. To identify candidate genes r...
ORGANISM(S): Mus musculus 
2010-03-31 | E-GEOD-19532 | biostudies-arrayexpress
TranscriptomicsProtein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I
Segregation of homologous maternal and paternal centromeres to opposite poles during meiosis I depends on post-replicative crossing over between homologous non-sister chromatids, which creates chiasmata and therefore bivalent chromosomes. Destruction of sister chromatid cohesion along chromosome arm...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-11 | E-GEOD-4791 | biostudies-arrayexpress
ProteomicsGlobal phosphoproteomic analysis of mouse spermatocytes identified key kinases regulating meiosis
Protein phosphorylation, as one of the most important post-translational modifications, exerts crucial roles in regulating meiosis. However, there is a lack of systemic phosphoproteomic and functional analysis of phosphorylation in the meiosis of spermatocytes. To characterize the phosphorylation ev...
ORGANISM(S): Mus Musculus 
2022-03-07 | PXD032089 |
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